Review


DOI :10.18017/iuitfd.382765   IUP :10.18017/iuitfd.382765    Full Text (PDF)

MEDICAL TREATMENT OF LEIOMYOMAS

Funda Güngör UğurlucanÖmer DemirCenk YaşaÖzlem Dural

Leiomyomas are the most common benign gynecological tumors observed during the reproductive period. Although, they are exceedingly common, not all are symptomatic. Leiomyomas are of genetic or hormonal origin and have estrogen and progesterone receptors, making them sensitive to hormones. The main treatment for leiomyomas is surgery, but in women who are not willing to undergo surgery or who want to preserve their fertility, medical treatment options may be used. The main basis of medical treatment in leiomyomas are hormones due to positive response to anti-hormonal therapies. Medical treatment options comprise gonadotropin-releasing-hormone agonists and antagonists, aromatase inhibitors, and selective progesterone receptor modulators. In addition to controlling bleeding, these treatment regimens cause a decrease in the volume of the tumor. In this review, treatment options are discussed.

DOI :10.18017/iuitfd.382765   IUP :10.18017/iuitfd.382765    Full Text (PDF)

LEİOMYOMLARIN MEDİKAL TEDAVİSİ

Funda Güngör UğurlucanÖmer DemirCenk YaşaÖzlem Dural

Leiomyomlar, reprodüktif çağda en sık görülen jinekolojik tümörlerdir. Leiomyomlar çoğu kadında bulunmakla beraber, bazı kadınlarda semptomatik hale gelmektedir. Genetik veya hormonal kökenli olabilirler. Leiomyomların üzerinde östrojen ve progesteron reseptörleri olması, onları hormona duyarlı hale getirmektedir. Leiomyomların ana tedavisi cerrahi olmakla beraber, cerrahi istemeyen veya fertilitesini korumak isteyen kadınlarda medikal tedaviler gündeme gelmektedir. Medikal tedavilerin çıkış noktası, leiomyomların hormona duyarlı olmasıdır. Medikal tedavi seçenekleri arasında gonadotropin-releasing-3 hormon analogları ve antagonistleri, aromataz inhibitörleri ve selektif progesteron reseptör modülatörleri yer almaktadır. Bu tedaviler kanama kontrolünün yanında leiomyom volümünde de küçülme sağlamaktadır. Bu derlemede bu tedavi yöntemlerine değinilecektir.


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APA

Güngör Uğurlucan, F., Demir, Ö., Yaşa, C., & Dural, Ö. (2017). MEDICAL TREATMENT OF LEIOMYOMAS. Journal of Istanbul Faculty of Medicine, 80(4), 153-161. https://doi.org/10.18017/iuitfd.382765


AMA

Güngör Uğurlucan F, Demir Ö, Yaşa C, Dural Ö. MEDICAL TREATMENT OF LEIOMYOMAS. Journal of Istanbul Faculty of Medicine. 2017;80(4):153-161. https://doi.org/10.18017/iuitfd.382765


ABNT

Güngör Uğurlucan, F.; Demir, Ö.; Yaşa, C.; Dural, Ö. MEDICAL TREATMENT OF LEIOMYOMAS. Journal of Istanbul Faculty of Medicine, [Publisher Location], v. 80, n. 4, p. 153-161, 2017.


Chicago: Author-Date Style

Güngör Uğurlucan, Funda, and Ömer Demir and Cenk Yaşa and Özlem Dural. 2017. “MEDICAL TREATMENT OF LEIOMYOMAS.” Journal of Istanbul Faculty of Medicine 80, no. 4: 153-161. https://doi.org/10.18017/iuitfd.382765


Chicago: Humanities Style

Güngör Uğurlucan, Funda, and Ömer Demir and Cenk Yaşa and Özlem Dural. MEDICAL TREATMENT OF LEIOMYOMAS.” Journal of Istanbul Faculty of Medicine 80, no. 4 (May. 2024): 153-161. https://doi.org/10.18017/iuitfd.382765


Harvard: Australian Style

Güngör Uğurlucan, F & Demir, Ö & Yaşa, C & Dural, Ö 2017, 'MEDICAL TREATMENT OF LEIOMYOMAS', Journal of Istanbul Faculty of Medicine, vol. 80, no. 4, pp. 153-161, viewed 20 May. 2024, https://doi.org/10.18017/iuitfd.382765


Harvard: Author-Date Style

Güngör Uğurlucan, F. and Demir, Ö. and Yaşa, C. and Dural, Ö. (2017) ‘MEDICAL TREATMENT OF LEIOMYOMAS’, Journal of Istanbul Faculty of Medicine, 80(4), pp. 153-161. https://doi.org/10.18017/iuitfd.382765 (20 May. 2024).


MLA

Güngör Uğurlucan, Funda, and Ömer Demir and Cenk Yaşa and Özlem Dural. MEDICAL TREATMENT OF LEIOMYOMAS.” Journal of Istanbul Faculty of Medicine, vol. 80, no. 4, 2017, pp. 153-161. [Database Container], https://doi.org/10.18017/iuitfd.382765


Vancouver

Güngör Uğurlucan F, Demir Ö, Yaşa C, Dural Ö. MEDICAL TREATMENT OF LEIOMYOMAS. Journal of Istanbul Faculty of Medicine [Internet]. 20 May. 2024 [cited 20 May. 2024];80(4):153-161. Available from: https://doi.org/10.18017/iuitfd.382765 doi: 10.18017/iuitfd.382765


ISNAD

Güngör Uğurlucan, Funda - Demir, Ömer - Yaşa, Cenk - Dural, Özlem. MEDICAL TREATMENT OF LEIOMYOMAS”. Journal of Istanbul Faculty of Medicine 80/4 (May. 2024): 153-161. https://doi.org/10.18017/iuitfd.382765



TIMELINE


Submitted01.08.2016
Accepted05.10.2017
Published Online20.12.2017

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