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DOI :10.26650/IUITFD.2019.0011   IUP :10.26650/IUITFD.2019.0011    Full Text (PDF)

GENETIC SYNDROMES AS A CAUSE OF TREATMENT RESISTANCE IN SCHIZOPHRENIA: A CASE WITH TRIPLE X SYNDROME

Bahadır Turan, Mehmet Akif Akıncı, İbrahim Selçuk Esin, Onur Burak Dursun

Triple X syndrome (47, XXX) is a numerical chromosomal alteration that affects 1/1.000 females, in which the individual is born with an extra X chromosome. Trisomy X is a relatively common but under- recognized chromosomal disorder associated with characteristic cognitive and behavioural features of varying severity. We report a 16-year old patient with Triple X syndrome and resistant schizophrenia. It is remarkable that genetic syndromes may be associated with resistance to treatment of psychiatric problems. Therefore in cases with treatment resistance, the genetic analysis should absolutely be examined. 
Keywords: Schizophrenia, treatment resistance, Triple X syndrome
DOI :10.26650/IUITFD.2019.0011   IUP :10.26650/IUITFD.2019.0011    Full Text (PDF)

ŞİZOFRENİDE TEDAVİYE DİRENÇ NEDENİ OLARAK GENETİK SENDROMLAR: TRİPLE X SENDROMLU BİR OLGU

Bahadır Turan, Mehmet Akif Akıncı, İbrahim Selçuk Esin, Onur Burak Dursun

Amaç: Triple X sendromu (47, XXX), kadınlarda ekstra bir X kromozomunun varlığı ile karakterize, 1/1.000 kişide bir görülen bir sendromdur. Trizomi X, değişken şiddette bilişsel ve davranışsal özelliklerle karakterize bir kromozomal hastalıktır. Bu olgu sunumunda; Triple X sendromlu ve dirençli şizofreni tanısı alan 16 yaşında bir vaka sunuyoruz. Genetik sendromların psikiyatrik problemlerin tedavisinde tedaviye dirençle ilişkili olabileceği ve bu nedenle tedaviye dirençli olgularda genetik analizlerin mutlaka yapılması gerektiği göz önünde bulundurulmalıdır. 
Keywords: Şizofreni, tedaviye direnç, Triple X sendrom

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References

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Citations

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APA

Turan, B., Akıncı, M., Esin, İ.S., & Dursun, O. (2019). GENETIC SYNDROMES AS A CAUSE OF TREATMENT RESISTANCE IN SCHIZOPHRENIA: A CASE WITH TRIPLE X SYNDROME. Journal of Istanbul Faculty of Medicine, 82(3), 162-163. https://doi.org/10.26650/IUITFD.2019.0011


AMA

Turan B, Akıncı M, Esin İ S, Dursun O. GENETIC SYNDROMES AS A CAUSE OF TREATMENT RESISTANCE IN SCHIZOPHRENIA: A CASE WITH TRIPLE X SYNDROME. Journal of Istanbul Faculty of Medicine. 2019;82(3):162-163. https://doi.org/10.26650/IUITFD.2019.0011


ABNT

Turan, B.; Akıncı, M.; Esin, İ.S.; Dursun, O. GENETIC SYNDROMES AS A CAUSE OF TREATMENT RESISTANCE IN SCHIZOPHRENIA: A CASE WITH TRIPLE X SYNDROME. Journal of Istanbul Faculty of Medicine, [Publisher Location], v. 82, n. 3, p. 162-163, 2019.


Chicago: Author-Date Style

Turan, Bahadır, and Mehmet Akif Akıncı and İbrahim Selçuk Esin and Onur Burak Dursun. 2019. “GENETIC SYNDROMES AS A CAUSE OF TREATMENT RESISTANCE IN SCHIZOPHRENIA: A CASE WITH TRIPLE X SYNDROME.” Journal of Istanbul Faculty of Medicine 82, no. 3: 162-163. https://doi.org/10.26650/IUITFD.2019.0011


Chicago: Humanities Style

Turan, Bahadır, and Mehmet Akif Akıncı and İbrahim Selçuk Esin and Onur Burak Dursun. “GENETIC SYNDROMES AS A CAUSE OF TREATMENT RESISTANCE IN SCHIZOPHRENIA: A CASE WITH TRIPLE X SYNDROME.” Journal of Istanbul Faculty of Medicine 82, no. 3 (May. 2025): 162-163. https://doi.org/10.26650/IUITFD.2019.0011


Harvard: Australian Style

Turan, B & Akıncı, M & Esin, İS & Dursun, O 2019, 'GENETIC SYNDROMES AS A CAUSE OF TREATMENT RESISTANCE IN SCHIZOPHRENIA: A CASE WITH TRIPLE X SYNDROME', Journal of Istanbul Faculty of Medicine, vol. 82, no. 3, pp. 162-163, viewed 23 May. 2025, https://doi.org/10.26650/IUITFD.2019.0011


Harvard: Author-Date Style

Turan, B. and Akıncı, M. and Esin, İ.S. and Dursun, O. (2019) ‘GENETIC SYNDROMES AS A CAUSE OF TREATMENT RESISTANCE IN SCHIZOPHRENIA: A CASE WITH TRIPLE X SYNDROME’, Journal of Istanbul Faculty of Medicine, 82(3), pp. 162-163. https://doi.org/10.26650/IUITFD.2019.0011 (23 May. 2025).


MLA

Turan, Bahadır, and Mehmet Akif Akıncı and İbrahim Selçuk Esin and Onur Burak Dursun. “GENETIC SYNDROMES AS A CAUSE OF TREATMENT RESISTANCE IN SCHIZOPHRENIA: A CASE WITH TRIPLE X SYNDROME.” Journal of Istanbul Faculty of Medicine, vol. 82, no. 3, 2019, pp. 162-163. [Database Container], https://doi.org/10.26650/IUITFD.2019.0011


Vancouver

Turan B, Akıncı M, Esin İS, Dursun O. GENETIC SYNDROMES AS A CAUSE OF TREATMENT RESISTANCE IN SCHIZOPHRENIA: A CASE WITH TRIPLE X SYNDROME. Journal of Istanbul Faculty of Medicine [Internet]. 23 May. 2025 [cited 23 May. 2025];82(3):162-163. Available from: https://doi.org/10.26650/IUITFD.2019.0011 doi: 10.26650/IUITFD.2019.0011


ISNAD

Turan, Bahadır - Akıncı, Mehmet Akif - Esin, İbrahimSelçuk - Dursun, Onur Burak. “GENETIC SYNDROMES AS A CAUSE OF TREATMENT RESISTANCE IN SCHIZOPHRENIA: A CASE WITH TRIPLE X SYNDROME”. Journal of Istanbul Faculty of Medicine 82/3 (May. 2025): 162-163. https://doi.org/10.26650/IUITFD.2019.0011



TIMELINE


Submitted24.01.2019
Accepted04.03.2019
Published Online19.06.2019

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