Journal of Istanbul Faculty of Medicine

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Research Article


DOI :10.26650/IUITFD.2019.0032   IUP :10.26650/IUITFD.2019.0032    Full Text (PDF)

TRANSPLANT RENAL ARTERY STENOSIS: SINGLE CENTER EXPERIENCE

Ali Burak Haras, Serap Yadigar, Pınar Özdemir, Çağlar Özer Aydın, Ergün Parmaksız, Meral Meşe, Serkan Feyyaz Yalın, Zerrin Bicik Bahçebaşı

Objective: Transplant renal artery stenosis (TRAS) and post-transplant arterial hypertension is a treatable cause of allograft dysfunction and graft loss. The risk factors for the development of TRAS include: donor age, prolonged and delayed graft function, cold ischemia time,concomitant CMV infection and surgical technique. Percutaneous transluminal angioplasty (PTA) has proven successful in treating TRAS in 60-90% of cases by providing renal reperfusion. In this study,we evaluated six TRAS cases in our clinic. 

Material and Method: We evaluated patients retrospectively from medical records who underwent transplantation in 2017. We recorded the age, gender, creatinine, other findings during transplantation, and the demographic features of transplant patients with TRAS. 

Results: TRAS was reported in 6 of 26 cases. The presence of iliac artery stenosis associated with renal artery stenosis was seen in two patients with CMV PCR (+). Patients underwent PTA and stent implantation. The need for antihypertensive treatment of the patients lessened during follow-up. 

Conclusion: TRAS is one of the reasons for allograft dysfunction after kidney transplantation. For this reason it should be kept in mind when determining the cause of the allograft disfunction. In addition to other risk factors, surgical technique plays an important role in the development of TRAS. Graft function can be preserved with early intervention.
Keywords: Allograft dysfunction, hypertension, transplant renal artery stenosis
DOI :10.26650/IUITFD.2019.0032   IUP :10.26650/IUITFD.2019.0032    Full Text (PDF)

TRANSPLANT RENAL ARTER STENOZU: TEK MERKEZ DENEYİMİ

Ali Burak Haras, Serap Yadigar, Pınar Özdemir, Çağlar Özer Aydın, Ergün Parmaksız, Meral Meşe, Serkan Feyyaz Yalın, Zerrin Bicik Bahçebaşı

Amaç: Transplant renal arter stenozu (TRAS) ve posttransplant arterial hipertansiyon allograft disfonksiyon ve greft kaybının tedavi edilebilir bir nedenidir. TRAS gelişiminde risk faktörleri arasında donor yaşı, uzun sureli gecikmiş greft fonksiyonu, soğuk iskemi süresi, eşzamanlı CMV enfeksiyonu varlığı ve cerrahi teknik vardır. Perkütan Translüminal Anjioplasti (PTA) %60-90 vakada renal perfüzyonu sağlar. Bu çalışmamızda, kliniğimizdeki 6 TRAS vakasının özelliklerini inceledik. 

Gereç ve Yöntem: Kliniğimizde, 2017 yılında böbrek nakli yapılan hastalar tıbbi kayıtlardan inceledik. TRAS gelişen hastaların yaş, cinsiyet, nakil sırasındaki diğer bulguları ve demografik özellikleri kaydedildi. 

Bulgular: Yirmi altı vakanın altısında TRAS saptandı. İliak arter darlık varlığı ile birlikte renal arter stenozu olan 2 hastada CMV PCR pozitifliği saptandı. Hastalara PTA ve stent implantasyonu uygulandı. Takiplerde antihipertansif tedavi ihtiyacı azaldı. 

Sonuç: TRAS, böbrek nakli sonrasında allograft disfonksiyonun nedenlerinden biridir. Sonuç olarak allograft disfonksiyonda akılda tutulmalıdır. Diğer risk fatörlerine ek olarak, cerrahi teknik de TRAS gelişiminde önemli bir rol oynar. Greft fonksiyonu erken girişimle korunabilir. 
Keywords: Allograft disfonksiyonu, hipertansiyon, transplant renal arter stenozu

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APA

Haras, A.B., Yadigar, S., Özdemir, P., Aydın, Ç., Parmaksız, E., Meşe, M., Yalın, S., & Bicik Bahçebaşı, Z. (2020). TRANSPLANT RENAL ARTERY STENOSIS: SINGLE CENTER EXPERIENCE. Journal of Istanbul Faculty of Medicine, 83(1), 55-59. https://doi.org/10.26650/IUITFD.2019.0032


AMA

Haras A B, Yadigar S, Özdemir P, Aydın Ç, Parmaksız E, Meşe M, Yalın S, Bicik Bahçebaşı Z. TRANSPLANT RENAL ARTERY STENOSIS: SINGLE CENTER EXPERIENCE. Journal of Istanbul Faculty of Medicine. 2020;83(1):55-59. https://doi.org/10.26650/IUITFD.2019.0032


ABNT

Haras, A.B.; Yadigar, S.; Özdemir, P.; Aydın, Ç.; Parmaksız, E.; Meşe, M.; Yalın, S.; Bicik Bahçebaşı, Z. TRANSPLANT RENAL ARTERY STENOSIS: SINGLE CENTER EXPERIENCE. Journal of Istanbul Faculty of Medicine, [Publisher Location], v. 83, n. 1, p. 55-59, 2020.


Chicago: Author-Date Style

Haras, Ali Burak, and Serap Yadigar and Pınar Özdemir and Çağlar Özer Aydın and Ergün Parmaksız and Meral Meşe and Serkan Feyyaz Yalın and Zerrin Bicik Bahçebaşı. 2020. “TRANSPLANT RENAL ARTERY STENOSIS: SINGLE CENTER EXPERIENCE.” Journal of Istanbul Faculty of Medicine 83, no. 1: 55-59. https://doi.org/10.26650/IUITFD.2019.0032


Chicago: Humanities Style

Haras, Ali Burak, and Serap Yadigar and Pınar Özdemir and Çağlar Özer Aydın and Ergün Parmaksız and Meral Meşe and Serkan Feyyaz Yalın and Zerrin Bicik Bahçebaşı. “TRANSPLANT RENAL ARTERY STENOSIS: SINGLE CENTER EXPERIENCE.” Journal of Istanbul Faculty of Medicine 83, no. 1 (Oct. 2024): 55-59. https://doi.org/10.26650/IUITFD.2019.0032


Harvard: Australian Style

Haras, AB & Yadigar, S & Özdemir, P & Aydın, Ç & Parmaksız, E & Meşe, M & Yalın, S & Bicik Bahçebaşı, Z 2020, 'TRANSPLANT RENAL ARTERY STENOSIS: SINGLE CENTER EXPERIENCE', Journal of Istanbul Faculty of Medicine, vol. 83, no. 1, pp. 55-59, viewed 24 Oct. 2024, https://doi.org/10.26650/IUITFD.2019.0032


Harvard: Author-Date Style

Haras, A.B. and Yadigar, S. and Özdemir, P. and Aydın, Ç. and Parmaksız, E. and Meşe, M. and Yalın, S. and Bicik Bahçebaşı, Z. (2020) ‘TRANSPLANT RENAL ARTERY STENOSIS: SINGLE CENTER EXPERIENCE’, Journal of Istanbul Faculty of Medicine, 83(1), pp. 55-59. https://doi.org/10.26650/IUITFD.2019.0032 (24 Oct. 2024).


MLA

Haras, Ali Burak, and Serap Yadigar and Pınar Özdemir and Çağlar Özer Aydın and Ergün Parmaksız and Meral Meşe and Serkan Feyyaz Yalın and Zerrin Bicik Bahçebaşı. “TRANSPLANT RENAL ARTERY STENOSIS: SINGLE CENTER EXPERIENCE.” Journal of Istanbul Faculty of Medicine, vol. 83, no. 1, 2020, pp. 55-59. [Database Container], https://doi.org/10.26650/IUITFD.2019.0032


Vancouver

Haras AB, Yadigar S, Özdemir P, Aydın Ç, Parmaksız E, Meşe M, Yalın S, Bicik Bahçebaşı Z. TRANSPLANT RENAL ARTERY STENOSIS: SINGLE CENTER EXPERIENCE. Journal of Istanbul Faculty of Medicine [Internet]. 24 Oct. 2024 [cited 24 Oct. 2024];83(1):55-59. Available from: https://doi.org/10.26650/IUITFD.2019.0032 doi: 10.26650/IUITFD.2019.0032


ISNAD

Haras, AliBurak - Yadigar, Serap - Özdemir, Pınar - Aydın, Çağlar Özer - Parmaksız, Ergün - Meşe, Meral - Yalın, Serkan Feyyaz - Bicik Bahçebaşı, Zerrin. “TRANSPLANT RENAL ARTERY STENOSIS: SINGLE CENTER EXPERIENCE”. Journal of Istanbul Faculty of Medicine 83/1 (Oct. 2024): 55-59. https://doi.org/10.26650/IUITFD.2019.0032



TIMELINE


Submitted05.04.2019
Accepted21.06.2019
Published Online13.01.2020

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