Journal of Child

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Research Article


DOI :10.5222/j.child.2010.069   IUP :10.5222/j.child.2010.069    Full Text (PDF)

Evalution of Term Newborns Hospitalized in Our NICU with the Diagnosis of Indirect Hyperbilirubinemia

Fatih Bolat, Sinan Uslu, Ali Bülbül, Serdar Cömert, Emrah Can, Asiye Nuhoğlu

Aim: To evaluate the clinical and demographic features, duration of treatment and risk factors in term newborns hospitalized with a diagnosis of indirect hyperbilirubinemia. Materials and Method: All term neonates, hospitalized with a diagnosis of indirect hyperbilirubinemia between January 2008 - December 2008 were included in the study. The patients in the study group were followed up for a year in respect to the complications of hyperbilirubinemia. Results: Two hundred and forty eight neonates, who met the inclusion criteria were evaluated. One hundred and forty five (58.5 %) neonates were males. The average gestational age and birth weight were found to be 38.1±1.0 weeks and 3025±509 g respectively. Of the 248 neonates, 136 (55.6 %) were the first child of the family and 198 (80 %) were exclusively breast fed. The average postnatal age at admission and total bilirubin level were 4.6±2.6 days and 18.7±4.5 mg/dL respectively. In 98 (39.5 %) neonates the etiology of hyperbilirubinemia could not be found. Dehydration was found in 33 (13.3 %), ABO incompatability in 75 (30.2 %) and Rh incompatability in 19 (7.2 %) patients. The average length of stay and duration of phototherapy were 3.1±2.2 days and 44.8±22.8 hours respectively. Nine patients received IVIG; of which 6 had Rh incompatability, 2 ABO incompatability and 1 subgorup incompatability. Exchange transfusion was performed in 8 patients. Two patients receiving IVIG had to be treated with exchange transfusion. During 1 year follow up any bilirubin encephalopathy, hearing loss or neuromotor developmental delay was not observed. Conclusion: Birth weight less than 2500 g, postnatal pathological weight loss and exclusive breastfeeding (p<0.05) were found to be the risk factors related with high total serum bilirubin levels. During one year follow up, absence of any developmental delay, hearing problem or bilirubin encephalopathy may indicate that optimum treatment and follow up have been accomplished for these newborns.

Keywords: Indirect hyperbilirubinemia, term newborn, hospitalization, dehydratation, risk factors
DOI :10.5222/j.child.2010.069   IUP :10.5222/j.child.2010.069    Full Text (PDF)

Yenidoğan Ünitemizde İndirekt Hiperbilirubinemi Tanısı ile Yatırılan Term Yenidoğan Bebeklerin Değerlendirilmesi

Fatih Bolat, Sinan Uslu, Ali Bülbül, Serdar Cömert, Emrah Can, Asiye Nuhoğlu

Amaç: İndirekt hiperbilirubinemi tanısıyla yatırılan term yenidoğanların klinik ve demografik özellikleri, tedavi süreleri ve risk faktörlerinin araştırılması. Gereç ve Yöntem: İndirekt hiperbilirubinemi tanısı ile Ocak 2008-Aralık 2008 tarihleri arasında hastaneye yatırılan term yenidoğanlar çalışmaya alındı. Bir yıl boyunca hiperbilirubinemi komplikasyonları açısından izlendi. Bulgular: Çalışma kriterlerine uyan 248 bebek değerlendirildi. Hastaların 145’i (% 58.5) erkekti. Hastaların doğum haftası 38.1±1.0 hafta, doğum ağırlığı 3025±509 g olarak saptandı. Bebeklerin 136’sı (% 55.6) ailenin ilk çocuğu idi. Vakaların 198’i (% 80) yalnızca anne sütü alıyordu. Başvuru zamanı 4.6±2.6 gün, total bilirubin düzeyi 18.7±4.5 mg/dL idi. Hastaların 98’inde (% 39.5) neden bulunamaz iken, 33’ünde (%13,3) dehidratasyon, 75’inde (% 30.2) ABO uyuşmazlığı ve 19’unda (% 7.2) Rh uygunsuzluğu vardı. Ortalama yatış 3.1±2.2 gün ve fototerapi süresi 44.8±22.8 saat olarak bulundu. Dokuz hastaya intravenöz immünglobulin verildi. Bunların 6’sında Rh uygunsuzluğu, 2’sinde ABO uygunsuzluğu, 1’inde subgrup uygunsuzluğu vardı. Sekiz hastaya kan değişimi yapıldı. İki hastaya IVIG verilmesine rağmen kan değişimi yapıldı. Bir yıllık izlemde akut bilirubin ensefalopatisi, işitme kaybı veya nöromotor gelişme geriliği saptanmadı. Sonuç: Hiperbilirubinemi gelişen term bebeklerde total serum bilirubin değeri üzerine doğum ağırlığının <2,500 g olması, patolojik tartı kaybı ve yalnızca anne sütü ile beslenmenin risk faktörleri olduğu saptandı. Bebeklerin bir yıllık izleminde hiperbilirubinemiye bağlı bir komplikasyonun saptanmaması bu bebeklere zamanında izlem ve uygun tedavi yöntemlerinin uygulandığını göstermektedir. 

Keywords: İndirekt hiperbilirubinemi, term yenidoğan, hastaneye yatış, dehidratasyon, risk faktörleri

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APA

Bolat, F., Uslu, S., Bülbül, A., Cömert, S., Can, E., & Nuhoğlu, A. (2010). Evalution of Term Newborns Hospitalized in Our NICU with the Diagnosis of Indirect Hyperbilirubinemia. Journal of Child, 10(2), 69-74. https://doi.org/10.5222/j.child.2010.069


AMA

Bolat F, Uslu S, Bülbül A, Cömert S, Can E, Nuhoğlu A. Evalution of Term Newborns Hospitalized in Our NICU with the Diagnosis of Indirect Hyperbilirubinemia. Journal of Child. 2010;10(2):69-74. https://doi.org/10.5222/j.child.2010.069


ABNT

Bolat, F.; Uslu, S.; Bülbül, A.; Cömert, S.; Can, E.; Nuhoğlu, A. Evalution of Term Newborns Hospitalized in Our NICU with the Diagnosis of Indirect Hyperbilirubinemia. Journal of Child, [Publisher Location], v. 10, n. 2, p. 69-74, 2010.


Chicago: Author-Date Style

Bolat, Fatih, and Sinan Uslu and Ali Bülbül and Serdar Cömert and Emrah Can and Asiye Nuhoğlu. 2010. “Evalution of Term Newborns Hospitalized in Our NICU with the Diagnosis of Indirect Hyperbilirubinemia.” Journal of Child 10, no. 2: 69-74. https://doi.org/10.5222/j.child.2010.069


Chicago: Humanities Style

Bolat, Fatih, and Sinan Uslu and Ali Bülbül and Serdar Cömert and Emrah Can and Asiye Nuhoğlu. “Evalution of Term Newborns Hospitalized in Our NICU with the Diagnosis of Indirect Hyperbilirubinemia.” Journal of Child 10, no. 2 (Nov. 2024): 69-74. https://doi.org/10.5222/j.child.2010.069


Harvard: Australian Style

Bolat, F & Uslu, S & Bülbül, A & Cömert, S & Can, E & Nuhoğlu, A 2010, 'Evalution of Term Newborns Hospitalized in Our NICU with the Diagnosis of Indirect Hyperbilirubinemia', Journal of Child, vol. 10, no. 2, pp. 69-74, viewed 14 Nov. 2024, https://doi.org/10.5222/j.child.2010.069


Harvard: Author-Date Style

Bolat, F. and Uslu, S. and Bülbül, A. and Cömert, S. and Can, E. and Nuhoğlu, A. (2010) ‘Evalution of Term Newborns Hospitalized in Our NICU with the Diagnosis of Indirect Hyperbilirubinemia’, Journal of Child, 10(2), pp. 69-74. https://doi.org/10.5222/j.child.2010.069 (14 Nov. 2024).


MLA

Bolat, Fatih, and Sinan Uslu and Ali Bülbül and Serdar Cömert and Emrah Can and Asiye Nuhoğlu. “Evalution of Term Newborns Hospitalized in Our NICU with the Diagnosis of Indirect Hyperbilirubinemia.” Journal of Child, vol. 10, no. 2, 2010, pp. 69-74. [Database Container], https://doi.org/10.5222/j.child.2010.069


Vancouver

Bolat F, Uslu S, Bülbül A, Cömert S, Can E, Nuhoğlu A. Evalution of Term Newborns Hospitalized in Our NICU with the Diagnosis of Indirect Hyperbilirubinemia. Journal of Child [Internet]. 14 Nov. 2024 [cited 14 Nov. 2024];10(2):69-74. Available from: https://doi.org/10.5222/j.child.2010.069 doi: 10.5222/j.child.2010.069


ISNAD

Bolat, Fatih - Uslu, Sinan - Bülbül, Ali - Cömert, Serdar - Can, Emrah - Nuhoğlu, Asiye. “Evalution of Term Newborns Hospitalized in Our NICU with the Diagnosis of Indirect Hyperbilirubinemia”. Journal of Child 10/2 (Nov. 2024): 69-74. https://doi.org/10.5222/j.child.2010.069



TIMELINE


Published Online30.12.2010

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