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DOI :10.17096/jiufd.90144   IUP :10.17096/jiufd.90144    Tam Metin (PDF)

PERİODONTAL TEDAVİDE KULLANILAN ANTİBİYOTİKLER

Ece BarçaEmine ÇifcibaşıSerdar Çintan

Periodontal hastalıklar periodontal dokuların doku yıkımına yol açan, karışık mikrobiyal etyolojisi ve belirgin inflamatuvar yanıt ile karakterize enfeksiyöz hastalıklardır. Periodontal tedavinin amacı, hastalık ile ilişkili patojenlerin ortadan kaldırılması ve periodontal sağlığın elde edilmesidir. Periodontitis tedavisi genellikle cerrahi olmayan mekanik debridman ve düzenli periodontal bakım ile yapılır. Periodontal cerrahi bazı hastalarda kök yüzeyine erişimi artırmak için endike olabilir; ancak, yalnız mekanik debridman tüm durumlarda yarar sağlamayabilir. Bu tür durumlarda, ilave antibiyotik tedavisi düşünülebilir. Böylece, serum ile derin periodontal cepler ve furkasyon alanlarının tabanında mikroorganizmalara ulaşım ve aynı zamanda dişeti epiteli ve bağ dokusu içinde bulunan organizmalara etki sağlanır. Bu derlemede, periodontal hastalıkta ne zaman ve hangi durumlarda sistemik antibiyotik reçete edilmesi gerektiği üzerine güncel klinik yaklaşımlar değerlendirilmiştir. Etki mekanizmaları, duyarlı periodontal patojenler, dozaj, periodontal hastalıkların tedavisinde kullanımı ve her antibiyotik için bakteri direnç mekanizması tartışılmıştır.

DOI :10.17096/jiufd.90144   IUP :10.17096/jiufd.90144    Tam Metin (PDF)

ADJUNCTIVE USE OF ANTIBIOTICS IN PERIODONTAL THERAPY

Ece BarçaEmine ÇifcibaşıSerdar Çintan

Periodontal diseases are infectious diseases with a mixed microbial aetiology and marked inflammatory response leading to destruction of underlying tissue. Periodontal therapy aims to eliminate pathogens associated with the disease and attain periodontal health. Periodontitis is generally treated by nonsurgical mechanical debridement and regular periodontal maintenance care. Periodontal surgery may be indicated for some patients to improve access to the root surface; however, mechanical debridement alone may not be helpful in all cases. In such cases, adjunctive systemic antibiotic therapy remains the treatment of choice. It can reach microorganisms at the base of the deep periodontal pockets and furcation areas via serum, and also affects organisms residing within gingival epithelium and connective tissue. This review aims to provide an update on clinical issues regarding when and how to prescribe systemic antibiotics in periodontal therapy. The points discussed are the mode of antibiotic action, susceptible periodontal pathogens, antibiotic dosage, antibiotic use in treatment of periodontal disease, and mechanism of bacterial resistance to each antibiotic.


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DIŞA AKTAR



APA

Barça, E., Çifcibaşı, E., & Çintan, S. (2015). PERİODONTAL TEDAVİDE KULLANILAN ANTİBİYOTİKLER. European Oral Research, 49(3), 55-62. https://doi.org/10.17096/jiufd.90144


AMA

Barça E, Çifcibaşı E, Çintan S. PERİODONTAL TEDAVİDE KULLANILAN ANTİBİYOTİKLER. European Oral Research. 2015;49(3):55-62. https://doi.org/10.17096/jiufd.90144


ABNT

Barça, E.; Çifcibaşı, E.; Çintan, S. PERİODONTAL TEDAVİDE KULLANILAN ANTİBİYOTİKLER. European Oral Research, [Publisher Location], v. 49, n. 3, p. 55-62, 2015.


Chicago: Author-Date Style

Barça, Ece, and Emine Çifcibaşı and Serdar Çintan. 2015. “PERİODONTAL TEDAVİDE KULLANILAN ANTİBİYOTİKLER.” European Oral Research 49, no. 3: 55-62. https://doi.org/10.17096/jiufd.90144


Chicago: Humanities Style

Barça, Ece, and Emine Çifcibaşı and Serdar Çintan. PERİODONTAL TEDAVİDE KULLANILAN ANTİBİYOTİKLER.” European Oral Research 49, no. 3 (Nov. 2024): 55-62. https://doi.org/10.17096/jiufd.90144


Harvard: Australian Style

Barça, E & Çifcibaşı, E & Çintan, S 2015, 'PERİODONTAL TEDAVİDE KULLANILAN ANTİBİYOTİKLER', European Oral Research, vol. 49, no. 3, pp. 55-62, viewed 22 Nov. 2024, https://doi.org/10.17096/jiufd.90144


Harvard: Author-Date Style

Barça, E. and Çifcibaşı, E. and Çintan, S. (2015) ‘PERİODONTAL TEDAVİDE KULLANILAN ANTİBİYOTİKLER’, European Oral Research, 49(3), pp. 55-62. https://doi.org/10.17096/jiufd.90144 (22 Nov. 2024).


MLA

Barça, Ece, and Emine Çifcibaşı and Serdar Çintan. PERİODONTAL TEDAVİDE KULLANILAN ANTİBİYOTİKLER.” European Oral Research, vol. 49, no. 3, 2015, pp. 55-62. [Database Container], https://doi.org/10.17096/jiufd.90144


Vancouver

Barça E, Çifcibaşı E, Çintan S. PERİODONTAL TEDAVİDE KULLANILAN ANTİBİYOTİKLER. European Oral Research [Internet]. 22 Nov. 2024 [cited 22 Nov. 2024];49(3):55-62. Available from: https://doi.org/10.17096/jiufd.90144 doi: 10.17096/jiufd.90144


ISNAD

Barça, Ece - Çifcibaşı, Emine - Çintan, Serdar. PERİODONTAL TEDAVİDE KULLANILAN ANTİBİYOTİKLER”. European Oral Research 49/3 (Nov. 2024): 55-62. https://doi.org/10.17096/jiufd.90144



ZAMAN ÇİZELGESİ


Gönderim09.09.2014
Kabul13.03.2015
Çevrimiçi Yayınlanma21.10.2015

PAYLAŞ




İstanbul Üniversitesi Yayınları, uluslararası yayıncılık standartları ve etiğine uygun olarak, yüksek kalitede bilimsel dergi ve kitapların yayınlanmasıyla giderek artan bilimsel bilginin yayılmasına katkıda bulunmayı amaçlamaktadır. İstanbul Üniversitesi Yayınları açık erişimli, ticari olmayan, bilimsel yayıncılığı takip etmektedir.