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DOI :10.26650/experimed.2019.19022   IUP :10.26650/experimed.2019.19022    Tam Metin (PDF)

Mezenkimal Kök Hücre Sinyal Yolakları ve Etkileşim Faktörleri

Gülsemin Çicek, Selçuk Duman, Tahsin Murad Aktan

Kök hücreler, farklı tip fonksiyonel hücrelere dönüşme potansiyeline sahip, kendi kendini yenileyebilen ve farklılaşmamış hücrelerdir. Bu hücreler, kökenleri temel alınarak iki ana tip olarak sınıflandırılabilir: Preimplante embriyonun iç hücre kitlesinden köken alan ve 3 germ yaprağını da yapılandırabilecek embriyonik kök hücreler ile farklı doku ve organlarda bulunan, en az bir tip fonksiyonel yapıya farklılaşabilme kapasitesine sahip erişkin kök hücreler. Bu her iki kök hücre tipi de çok farklı etkileşim faktörleri varlığında kendi sinyal yollarını kullanarak kendi özelliklerini ve kapasitelerini sunar. Bu kök hücrelerin özelliklerini ayrıntılı olarak bilmek, terapötik maddelere önemli katkı sağlayacaktır.

Anahtar Kelimeler: Kök hücre, sinyal yolağı, etkileşim faktörleri
DOI :10.26650/experimed.2019.19022   IUP :10.26650/experimed.2019.19022    Tam Metin (PDF)

Mesenchymal Stem Cell Signaling Pathway and Interaction Factors

Gülsemin Çicek, Selçuk Duman, Tahsin Murad Aktan

Stem cells are self-renewing and undifferentiated cells with potential to transform into different types of functional cells. These cells can be classified into two types based on their roots; embryonic stem cells that originate from the inner cell mass of preimplanted embryos and can structure the tree germinal layers and, mature stem cells that have the potential to differentiate into at least one type of functional structure. Both types of the stem cells present their own characteristics and capacities by using their own signal pathways in the presence of very different interaction factors. Knowing the characteristics of those stem cells in detail will importantly contribute to therapeutics. 

Anahtar Kelimeler: Stem cell, signal pathway, interaction factors

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APA

Çicek, G., Duman, S., & Aktan, T. (0001). Mezenkimal Kök Hücre Sinyal Yolakları ve Etkileşim Faktörleri. Experimed, 9(3), 120-129. https://doi.org/10.26650/experimed.2019.19022


AMA

Çicek G, Duman S, Aktan T. Mezenkimal Kök Hücre Sinyal Yolakları ve Etkileşim Faktörleri. Experimed. 0001;9(3):120-129. https://doi.org/10.26650/experimed.2019.19022


ABNT

Çicek, G.; Duman, S.; Aktan, T. Mezenkimal Kök Hücre Sinyal Yolakları ve Etkileşim Faktörleri. Experimed, [Publisher Location], v. 9, n. 3, p. 120-129, 0001.


Chicago: Author-Date Style

Çicek, Gülsemin, and Selçuk Duman and Tahsin Murad Aktan. 0001. “Mezenkimal Kök Hücre Sinyal Yolakları ve Etkileşim Faktörleri.” Experimed 9, no. 3: 120-129. https://doi.org/10.26650/experimed.2019.19022


Chicago: Humanities Style

Çicek, Gülsemin, and Selçuk Duman and Tahsin Murad Aktan. “Mezenkimal Kök Hücre Sinyal Yolakları ve Etkileşim Faktörleri.” Experimed 9, no. 3 (Dec. 2024): 120-129. https://doi.org/10.26650/experimed.2019.19022


Harvard: Australian Style

Çicek, G & Duman, S & Aktan, T 0001, 'Mezenkimal Kök Hücre Sinyal Yolakları ve Etkileşim Faktörleri', Experimed, vol. 9, no. 3, pp. 120-129, viewed 22 Dec. 2024, https://doi.org/10.26650/experimed.2019.19022


Harvard: Author-Date Style

Çicek, G. and Duman, S. and Aktan, T. (0001) ‘Mezenkimal Kök Hücre Sinyal Yolakları ve Etkileşim Faktörleri’, Experimed, 9(3), pp. 120-129. https://doi.org/10.26650/experimed.2019.19022 (22 Dec. 2024).


MLA

Çicek, Gülsemin, and Selçuk Duman and Tahsin Murad Aktan. “Mezenkimal Kök Hücre Sinyal Yolakları ve Etkileşim Faktörleri.” Experimed, vol. 9, no. 3, 0001, pp. 120-129. [Database Container], https://doi.org/10.26650/experimed.2019.19022


Vancouver

Çicek G, Duman S, Aktan T. Mezenkimal Kök Hücre Sinyal Yolakları ve Etkileşim Faktörleri. Experimed [Internet]. 22 Dec. 2024 [cited 22 Dec. 2024];9(3):120-129. Available from: https://doi.org/10.26650/experimed.2019.19022 doi: 10.26650/experimed.2019.19022


ISNAD

Çicek, Gülsemin - Duman, Selçuk - Aktan, Tahsin Murad. “Mezenkimal Kök Hücre Sinyal Yolakları ve Etkileşim Faktörleri”. Experimed 9/3 (Dec. 2024): 120-129. https://doi.org/10.26650/experimed.2019.19022



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Kabul23.10.2019

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