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DOI :10.26650/jchild.2023.1308863   IUP :10.26650/jchild.2023.1308863    Tam Metin (PDF)

30 Years of Wilms Tumor Experience at One Center in Türkiye’s Central Anatolia Region

Şefika Akyol, Gül Pelin Odabaş, Alper Özcan, Ebru Yılmaz, Zehra Filiz Karaman, Figen Öztürk, Hülya Akgün, Ahmet Burak Doğan, Celalettin Eroğlu, Ekrem Ünal, Musa Karakükcü

Objective: The current study aims to evaluate the clinical presentation, treatment, and follow-up of children with Wilms Tumor (WT) who had been admitted to Erciyes University, Faculty of Medicine Department of Pediatric Hematology and Oncology hospital, a tertiary center in the central Anatolia region of Türkiye. The study assesses the survival data and features that have had an impact on survival.

Materials and Methods: The current study has been planned as a retrospective observational evaluation of patients admitted to the Pediatric Hematology and Oncology Center between 1991-2021.

Results: The study retrospectively evaluated a total of 48 patients in terms of demographic characteristics, presentation findings, tumor stages, histopathologies, and survival rates. Patients with an unfavorable histology had a 66.7% chance of both event-free survival (EFS) and overall survival (OS), which is lower than the respective 85.2% and 92.1% odds of EFS and OS for the favorable histology group. However, this is not statistically significant (p = 0.20 for EFS and p = 0.05 for OS). Regarding the impact of stage on survival rates, the EFS and OS for patients with the low-stage disease were 88% and 95.7%, respectively. These rates were significantly superior to those at an advanced stage of the disease, whose EFS and OS were 63.1% and 60.9%, respectively (p = 0.042 for EFS, p = 0.005 for OS).

Conclusion: Wilms tumor at an advanced stage and with an unfavorable histology are the major factors resulting in poor survival rates.

Anahtar Kelimeler: Wilms Tumor, Event-Free Survival, Overall Survival, Unfavorable Histology

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DIŞA AKTAR



APA

Akyol, Ş., Odabaş, G.P., Özcan, A., Yılmaz, E., Karaman, Z.F., Öztürk, F., Akgün, H., Doğan, A.B., Eroğlu, C., Ünal, E., & Karakükcü, M. (2023). 30 Years of Wilms Tumor Experience at One Center in Türkiye’s Central Anatolia Region. Çocuk Dergisi, 23(4), 344-348. https://doi.org/10.26650/jchild.2023.1308863


AMA

Akyol Ş, Odabaş G P, Özcan A, Yılmaz E, Karaman Z F, Öztürk F, Akgün H, Doğan A B, Eroğlu C, Ünal E, Karakükcü M. 30 Years of Wilms Tumor Experience at One Center in Türkiye’s Central Anatolia Region. Çocuk Dergisi. 2023;23(4):344-348. https://doi.org/10.26650/jchild.2023.1308863


ABNT

Akyol, Ş.; Odabaş, G.P.; Özcan, A.; Yılmaz, E.; Karaman, Z.F.; Öztürk, F.; Akgün, H.; Doğan, A.B.; Eroğlu, C.; Ünal, E.; Karakükcü, M. 30 Years of Wilms Tumor Experience at One Center in Türkiye’s Central Anatolia Region. Çocuk Dergisi, [Publisher Location], v. 23, n. 4, p. 344-348, 2023.


Chicago: Author-Date Style

Akyol, Şefika, and Gül Pelin Odabaş and Alper Özcan and Ebru Yılmaz and Zehra Filiz Karaman and Figen Öztürk and Hülya Akgün and Ahmet Burak Doğan and Celalettin Eroğlu and Ekrem Ünal and Musa Karakükcü. 2023. “30 Years of Wilms Tumor Experience at One Center in Türkiye’s Central Anatolia Region.” Çocuk Dergisi 23, no. 4: 344-348. https://doi.org/10.26650/jchild.2023.1308863


Chicago: Humanities Style

Akyol, Şefika, and Gül Pelin Odabaş and Alper Özcan and Ebru Yılmaz and Zehra Filiz Karaman and Figen Öztürk and Hülya Akgün and Ahmet Burak Doğan and Celalettin Eroğlu and Ekrem Ünal and Musa Karakükcü. “30 Years of Wilms Tumor Experience at One Center in Türkiye’s Central Anatolia Region.” Çocuk Dergisi 23, no. 4 (Apr. 2024): 344-348. https://doi.org/10.26650/jchild.2023.1308863


Harvard: Australian Style

Akyol, Ş & Odabaş, GP & Özcan, A & Yılmaz, E & Karaman, ZF & Öztürk, F & Akgün, H & Doğan, AB & Eroğlu, C & Ünal, E & Karakükcü, M 2023, '30 Years of Wilms Tumor Experience at One Center in Türkiye’s Central Anatolia Region', Çocuk Dergisi, vol. 23, no. 4, pp. 344-348, viewed 28 Apr. 2024, https://doi.org/10.26650/jchild.2023.1308863


Harvard: Author-Date Style

Akyol, Ş. and Odabaş, G.P. and Özcan, A. and Yılmaz, E. and Karaman, Z.F. and Öztürk, F. and Akgün, H. and Doğan, A.B. and Eroğlu, C. and Ünal, E. and Karakükcü, M. (2023) ‘30 Years of Wilms Tumor Experience at One Center in Türkiye’s Central Anatolia Region’, Çocuk Dergisi, 23(4), pp. 344-348. https://doi.org/10.26650/jchild.2023.1308863 (28 Apr. 2024).


MLA

Akyol, Şefika, and Gül Pelin Odabaş and Alper Özcan and Ebru Yılmaz and Zehra Filiz Karaman and Figen Öztürk and Hülya Akgün and Ahmet Burak Doğan and Celalettin Eroğlu and Ekrem Ünal and Musa Karakükcü. “30 Years of Wilms Tumor Experience at One Center in Türkiye’s Central Anatolia Region.” Çocuk Dergisi, vol. 23, no. 4, 2023, pp. 344-348. [Database Container], https://doi.org/10.26650/jchild.2023.1308863


Vancouver

Akyol Ş, Odabaş GP, Özcan A, Yılmaz E, Karaman ZF, Öztürk F, Akgün H, Doğan AB, Eroğlu C, Ünal E, Karakükcü M. 30 Years of Wilms Tumor Experience at One Center in Türkiye’s Central Anatolia Region. Çocuk Dergisi [Internet]. 28 Apr. 2024 [cited 28 Apr. 2024];23(4):344-348. Available from: https://doi.org/10.26650/jchild.2023.1308863 doi: 10.26650/jchild.2023.1308863


ISNAD

Akyol, Şefika - Odabaş, GülPelin - Özcan, Alper - Yılmaz, Ebru - Karaman, ZehraFiliz - Öztürk, Figen - Akgün, Hülya - Doğan, AhmetBurak - Eroğlu, Celalettin - Ünal, Ekrem - Karakükcü, Musa. “30 Years of Wilms Tumor Experience at One Center in Türkiye’s Central Anatolia Region”. Çocuk Dergisi 23/4 (Apr. 2024): 344-348. https://doi.org/10.26650/jchild.2023.1308863



ZAMAN ÇİZELGESİ


Gönderim02.06.2023
Kabul25.07.2023
Çevrimiçi Yayınlanma20.12.2023

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