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DOI :10.26650/jchild.2024.1588249   IUP :10.26650/jchild.2024.1588249    Tam Metin (PDF)

Evaluation of the Clinical Phenotype and Follow-up of Children with ‘Non sustained’ Ventricular Tachycardia Detected on 24-hour Rhythm Holter

Serra Karaca, Doruk Özbingöl, Kazım Öztarhan, Kemal Nişli

Objective: Non-sustained ventricular tachycardia (NSVT) is an important arrhythmic finding in pediatric patients, with varying clinical implications based on the presence of structural heart disease. This study aimed to evaluate the clinical characteristics, follow-up, and management of children diagnosed with NSVT detected on 24-hour Holter monitoring.

Methods: A retrospective analysis was conducted on 22 pediatric patients (9 males, 13 females) aged 2.5–17 years, who were diagnosed with NSVT between 2015 and 2023. Patients with sustained VT, channelopathies, or electrolyte-related prolonged QTc were excluded. Echocardiography, electrocardiography, and Holter monitoring were performed for all patients. Statistical analyses were conducted using SPSS 26.0, with significance set at p<0.05.

Results: Monomorphic NSVT was observed in 14 patients (64%), while polymorphic NSVT was found in 8 patients (36%). The mean VT rate was 161.2±18.7 bpm, with polymorphic VT demonstrating a significantly higher rate (175.3±4.4 bpm) than monomorphic VT (153.3±4.6 bpm) (p=0.003). The prematurity index was significantly lower in polymorphic VT (0.75±0.03) than in monomorphic VT (1.1±0.03) (p<0.001). Additionally, QTc was longer in polymorphic VT (463.5±5.1 ms vs. 425.4±6.5 ms, p=0.004). Structural heart disease was present in 50% of cases, with polymorphic VT being predominantly associated with cardiomyopathies (dilated, hypertrophic, and non-compaction). Only three patients (14%) were symptomatic, and all symptomatic patients had structural heart disease. All patients with underlying cardiac abnormalities were treated with beta-blockers, primarily propranolol, while those with normal echocardiography were followed without medication. No adverse effects, syncope, or mortality were observed during follow-up.

Conclusion: NSVT in pediatric patients should be carefully evaluated, particularly in the presence of structural heart disease. While monomorphic NSVT in structurally normal hearts appears benign, polymorphic NSVT is strongly associated with cardiomyopathies, necessitating medical therapy and close monitoring. Individualized management based on echocardiographic findings and arrhythmic characteristics is essential for optimizing patient outcomes.

Anahtar Kelimeler: Non-sustained ventricular tachycardia, Holter monitoring, beta-blockers

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APA

Karaca, S., Özbingöl, D., Öztarhan, K., & Nişli, K. (2024). Evaluation of the Clinical Phenotype and Follow-up of Children with ‘Non sustained’ Ventricular Tachycardia Detected on 24-hour Rhythm Holter. Çocuk Dergisi, 24(4), 241-244. https://doi.org/10.26650/jchild.2024.1588249


AMA

Karaca S, Özbingöl D, Öztarhan K, Nişli K. Evaluation of the Clinical Phenotype and Follow-up of Children with ‘Non sustained’ Ventricular Tachycardia Detected on 24-hour Rhythm Holter. Çocuk Dergisi. 2024;24(4):241-244. https://doi.org/10.26650/jchild.2024.1588249


ABNT

Karaca, S.; Özbingöl, D.; Öztarhan, K.; Nişli, K. Evaluation of the Clinical Phenotype and Follow-up of Children with ‘Non sustained’ Ventricular Tachycardia Detected on 24-hour Rhythm Holter. Çocuk Dergisi, [Publisher Location], v. 24, n. 4, p. 241-244, 2024.


Chicago: Author-Date Style

Karaca, Serra, and Doruk Özbingöl and Kazım Öztarhan and Kemal Nişli. 2024. “Evaluation of the Clinical Phenotype and Follow-up of Children with ‘Non sustained’ Ventricular Tachycardia Detected on 24-hour Rhythm Holter.” Çocuk Dergisi 24, no. 4: 241-244. https://doi.org/10.26650/jchild.2024.1588249


Chicago: Humanities Style

Karaca, Serra, and Doruk Özbingöl and Kazım Öztarhan and Kemal Nişli. “Evaluation of the Clinical Phenotype and Follow-up of Children with ‘Non sustained’ Ventricular Tachycardia Detected on 24-hour Rhythm Holter.” Çocuk Dergisi 24, no. 4 (Mar. 2025): 241-244. https://doi.org/10.26650/jchild.2024.1588249


Harvard: Australian Style

Karaca, S & Özbingöl, D & Öztarhan, K & Nişli, K 2024, 'Evaluation of the Clinical Phenotype and Follow-up of Children with ‘Non sustained’ Ventricular Tachycardia Detected on 24-hour Rhythm Holter', Çocuk Dergisi, vol. 24, no. 4, pp. 241-244, viewed 10 Mar. 2025, https://doi.org/10.26650/jchild.2024.1588249


Harvard: Author-Date Style

Karaca, S. and Özbingöl, D. and Öztarhan, K. and Nişli, K. (2024) ‘Evaluation of the Clinical Phenotype and Follow-up of Children with ‘Non sustained’ Ventricular Tachycardia Detected on 24-hour Rhythm Holter’, Çocuk Dergisi, 24(4), pp. 241-244. https://doi.org/10.26650/jchild.2024.1588249 (10 Mar. 2025).


MLA

Karaca, Serra, and Doruk Özbingöl and Kazım Öztarhan and Kemal Nişli. “Evaluation of the Clinical Phenotype and Follow-up of Children with ‘Non sustained’ Ventricular Tachycardia Detected on 24-hour Rhythm Holter.” Çocuk Dergisi, vol. 24, no. 4, 2024, pp. 241-244. [Database Container], https://doi.org/10.26650/jchild.2024.1588249


Vancouver

Karaca S, Özbingöl D, Öztarhan K, Nişli K. Evaluation of the Clinical Phenotype and Follow-up of Children with ‘Non sustained’ Ventricular Tachycardia Detected on 24-hour Rhythm Holter. Çocuk Dergisi [Internet]. 10 Mar. 2025 [cited 10 Mar. 2025];24(4):241-244. Available from: https://doi.org/10.26650/jchild.2024.1588249 doi: 10.26650/jchild.2024.1588249


ISNAD

Karaca, Serra - Özbingöl, Doruk - Öztarhan, Kazım - Nişli, Kemal. “Evaluation of the Clinical Phenotype and Follow-up of Children with ‘Non sustained’ Ventricular Tachycardia Detected on 24-hour Rhythm Holter”. Çocuk Dergisi 24/4 (Mar. 2025): 241-244. https://doi.org/10.26650/jchild.2024.1588249



ZAMAN ÇİZELGESİ


Gönderim20.11.2024
Kabul03.01.2025

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