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DOI :10.26650/jchild.2024.1527424   IUP :10.26650/jchild.2024.1527424    Tam Metin (PDF)

Metabolic Syndrome and Type 2 Diabetes Mellitus in Overweight and Obese Children: A Single Centre Experience

Asuman Demirbuğa, Şükran Poyrazoğlu, Rüveyde Bundak

Objective: Childhood obesity is associated with various risks, including insulin resistance, type 2 diabetes mellitus (DM), hypertension, and metabolic syndrome (MetS). This study evaluated MetS and type 2 diabetes mellitus (DM) in overweight and obese children.

Methods: Between 2000 and 2013, 474 obese and overweight children aged <18 years were included in this study. The clinical characteristics of the patients with MetS and type 2 DM were evaluated.

Results: Of the patients, 50.4% (n = 239) were girls, and the mean age was 10.91±3.06 years. According to the body mass index, 20.5% (n=97) of the patients were overweight and 79.5% (n=377) were obese. Blood pressure, striae, and acanthosis nigricans were significantly higher in the obese group than in the overweight group (p <0.05). MetS was found in 30.8% (n=146) of the patients. The MetS rate was 37.7% (n=142) in the obese patients and 4.1% (n=4) in the overweight patients, and the difference between them was statistically significant (p<0.001) Based on the oral glucose tolerance test; 45 (9.5%) patients had impaired fasting glycaemia, 24 (5%) had impaired glucose tolerance and 4 (0.84%) had type 2 DM. One patient with normal glucose balance at admission, who was diagnosed with type 2 DM in the 4th year, was overweight and had a family history of diabetes, hyperinsulinemia, and high HOMA-IR.

Conclusions: The results of our study showed that both obese and overweight children are at risk of developing MetS and type 2 DM, particularly in the presence of risk factors. Close monitoring of these children is important to prevent complications. 

Anahtar Kelimeler: Childhood obesity, overweight, metabolic syndrome, type 2 diabetes mellitus

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APA

Demirbuğa, A., Poyrazoğlu, Ş., & Bundak, R. (2024). Metabolic Syndrome and Type 2 Diabetes Mellitus in Overweight and Obese Children: A Single Centre Experience. Çocuk Dergisi, 24(3), 154-161. https://doi.org/10.26650/jchild.2024.1527424


AMA

Demirbuğa A, Poyrazoğlu Ş, Bundak R. Metabolic Syndrome and Type 2 Diabetes Mellitus in Overweight and Obese Children: A Single Centre Experience. Çocuk Dergisi. 2024;24(3):154-161. https://doi.org/10.26650/jchild.2024.1527424


ABNT

Demirbuğa, A.; Poyrazoğlu, Ş.; Bundak, R. Metabolic Syndrome and Type 2 Diabetes Mellitus in Overweight and Obese Children: A Single Centre Experience. Çocuk Dergisi, [Publisher Location], v. 24, n. 3, p. 154-161, 2024.


Chicago: Author-Date Style

Demirbuğa, Asuman, and Şükran Poyrazoğlu and Rüveyde Bundak. 2024. “Metabolic Syndrome and Type 2 Diabetes Mellitus in Overweight and Obese Children: A Single Centre Experience.” Çocuk Dergisi 24, no. 3: 154-161. https://doi.org/10.26650/jchild.2024.1527424


Chicago: Humanities Style

Demirbuğa, Asuman, and Şükran Poyrazoğlu and Rüveyde Bundak. “Metabolic Syndrome and Type 2 Diabetes Mellitus in Overweight and Obese Children: A Single Centre Experience.” Çocuk Dergisi 24, no. 3 (Jan. 2025): 154-161. https://doi.org/10.26650/jchild.2024.1527424


Harvard: Australian Style

Demirbuğa, A & Poyrazoğlu, Ş & Bundak, R 2024, 'Metabolic Syndrome and Type 2 Diabetes Mellitus in Overweight and Obese Children: A Single Centre Experience', Çocuk Dergisi, vol. 24, no. 3, pp. 154-161, viewed 30 Jan. 2025, https://doi.org/10.26650/jchild.2024.1527424


Harvard: Author-Date Style

Demirbuğa, A. and Poyrazoğlu, Ş. and Bundak, R. (2024) ‘Metabolic Syndrome and Type 2 Diabetes Mellitus in Overweight and Obese Children: A Single Centre Experience’, Çocuk Dergisi, 24(3), pp. 154-161. https://doi.org/10.26650/jchild.2024.1527424 (30 Jan. 2025).


MLA

Demirbuğa, Asuman, and Şükran Poyrazoğlu and Rüveyde Bundak. “Metabolic Syndrome and Type 2 Diabetes Mellitus in Overweight and Obese Children: A Single Centre Experience.” Çocuk Dergisi, vol. 24, no. 3, 2024, pp. 154-161. [Database Container], https://doi.org/10.26650/jchild.2024.1527424


Vancouver

Demirbuğa A, Poyrazoğlu Ş, Bundak R. Metabolic Syndrome and Type 2 Diabetes Mellitus in Overweight and Obese Children: A Single Centre Experience. Çocuk Dergisi [Internet]. 30 Jan. 2025 [cited 30 Jan. 2025];24(3):154-161. Available from: https://doi.org/10.26650/jchild.2024.1527424 doi: 10.26650/jchild.2024.1527424


ISNAD

Demirbuğa, Asuman - Poyrazoğlu, Şükran - Bundak, Rüveyde. “Metabolic Syndrome and Type 2 Diabetes Mellitus in Overweight and Obese Children: A Single Centre Experience”. Çocuk Dergisi 24/3 (Jan. 2025): 154-161. https://doi.org/10.26650/jchild.2024.1527424



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Gönderim05.08.2024
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