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DOI :10.26650/IUITFD.2018.0026   IUP :10.26650/IUITFD.2018.0026    Tam Metin (PDF)

HPV TİP 16 VE 18 DIŞINDA POZİTİF, SMEAR SONUCU NORMAL HASTALARIN KOLPOSKOPİK İNCELENMESİ

Ramazan DenizliÖnder SakinAli Doğukan AnğınMuzaffer Seyhan ÇıkmanZehra Meltem Pirimoğlu

Amaç: Human Papilloma Virüs (HPV) tip 16 ve 18 dışında pozitifliği olup, smear sonucu normal olan hastaların kolposkopik muayene ve biyopsi sonuçlarını incelemek 

Gereç ve Yöntem: Çalışmamızda smear sonucu normal, ancak HPV tip 16-18 dışında pozitifliği olan ve Ocak 2017- Aralık 2017 tarihleri arasında hastanemizde kolposkopi yapılan 300 hasta incelendi. Hastalarımızın genel olarak kolposkopi endikasyonu postkoital kanama, ailede jinekolojik malignite öyküsü ve makroskopik şüpheli lezyon bulunması idi. Kolposkopi sırasında şüpheli lezyonu olmayan 39 hastaya (% 13) bir yıl sonra ko-test için kontrole çağrılırken, 261 hastaya kolposkopi kılavuzlu doku örneklemesi yapıldı. 

Bulgular: Histolojik inceleme sonuçları 186 hastada (%62) inflamasyon, 61 hastada (%20,33) CIN 1, 9 hastada (%3) CIN 2, 3 hastada (%1) CIN 3 ve 2 hastada (%0,67) servikal kanser olarak rapor edilmiştir. 

Sonuç: HPV tip 16-18 dışında pozitifliği olup smear sonucu normal olan hastalarda CIN 2 ve üstü lezyon, hatta kanser teşhisi konulabileceği unutulmamalıdır.
DOI :10.26650/IUITFD.2018.0026   IUP :10.26650/IUITFD.2018.0026    Tam Metin (PDF)

COLPOSCOPIC EXAMINATION IN CYTOLOGY NEGATIVE WOMEN WHO TESTED POSITIVE FOR NON-16/18 HPV TYPES

Ramazan DenizliÖnder SakinAli Doğukan AnğınMuzaffer Seyhan ÇıkmanZehra Meltem Pirimoğlu

Objective: To assess the colposcopic examination findings and biopsy results in women who tested positive for oncogenic Human Papilloma Virus (HPV) types other than HPV-16 and 18 while having otherwise normal Pap test results. 

Material and Method: This paper analyzes the results from a total of 300 women who tested positive for non-16/18 HPV types but had otherwise normal Pap test and underwent a colposcopic examination in our hospital between January 2017 and December 2017. The study subjects presented with postcoital bleeding, had a family history of cancer or exhibited macroscopic examination findings which were suspected to be malign. A co-test was scheduled one year later for 39 patients (13%) who had no lesions suspected of malignancy and a colposcopy-guided tissue sample was performed on 261 patients. 

Results: Histological examination results included inflammation (in 186 patients [62%]), CIN 1 (in 61 patients [20.33%]), CIN 2 (in 9 patients [3%], CIN 3 (in 3 patients [1%]) and cervical cancer (in 2 patients [%0.67]). 

Conclusion: One should keep in mind that a diagnosis of CIN 2 or more severe lesions or even cervical cancer can be made using a colposcopy-guided biopsy in women who test positive for non 16/18 HPV types but have otherwise normal Pap smear test. 

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DIŞA AKTAR



APA

Denizli, R., Sakin, Ö., Anğın, A.D., Çıkman, M., & Pirimoğlu, Z. (2019). HPV TİP 16 VE 18 DIŞINDA POZİTİF, SMEAR SONUCU NORMAL HASTALARIN KOLPOSKOPİK İNCELENMESİ. İstanbul Tıp Fakültesi Dergisi, 82(4), 212-218. https://doi.org/10.26650/IUITFD.2018.0026


AMA

Denizli R, Sakin Ö, Anğın A D, Çıkman M, Pirimoğlu Z. HPV TİP 16 VE 18 DIŞINDA POZİTİF, SMEAR SONUCU NORMAL HASTALARIN KOLPOSKOPİK İNCELENMESİ. İstanbul Tıp Fakültesi Dergisi. 2019;82(4):212-218. https://doi.org/10.26650/IUITFD.2018.0026


ABNT

Denizli, R.; Sakin, Ö.; Anğın, A.D.; Çıkman, M.; Pirimoğlu, Z. HPV TİP 16 VE 18 DIŞINDA POZİTİF, SMEAR SONUCU NORMAL HASTALARIN KOLPOSKOPİK İNCELENMESİ. İstanbul Tıp Fakültesi Dergisi, [Publisher Location], v. 82, n. 4, p. 212-218, 2019.


Chicago: Author-Date Style

Denizli, Ramazan, and Önder Sakin and Ali Doğukan Anğın and Muzaffer Seyhan Çıkman and Zehra Meltem Pirimoğlu. 2019. “HPV TİP 16 VE 18 DIŞINDA POZİTİF, SMEAR SONUCU NORMAL HASTALARIN KOLPOSKOPİK İNCELENMESİ.” İstanbul Tıp Fakültesi Dergisi 82, no. 4: 212-218. https://doi.org/10.26650/IUITFD.2018.0026


Chicago: Humanities Style

Denizli, Ramazan, and Önder Sakin and Ali Doğukan Anğın and Muzaffer Seyhan Çıkman and Zehra Meltem Pirimoğlu. HPV TİP 16 VE 18 DIŞINDA POZİTİF, SMEAR SONUCU NORMAL HASTALARIN KOLPOSKOPİK İNCELENMESİ.” İstanbul Tıp Fakültesi Dergisi 82, no. 4 (Apr. 2025): 212-218. https://doi.org/10.26650/IUITFD.2018.0026


Harvard: Australian Style

Denizli, R & Sakin, Ö & Anğın, AD & Çıkman, M & Pirimoğlu, Z 2019, 'HPV TİP 16 VE 18 DIŞINDA POZİTİF, SMEAR SONUCU NORMAL HASTALARIN KOLPOSKOPİK İNCELENMESİ', İstanbul Tıp Fakültesi Dergisi, vol. 82, no. 4, pp. 212-218, viewed 25 Apr. 2025, https://doi.org/10.26650/IUITFD.2018.0026


Harvard: Author-Date Style

Denizli, R. and Sakin, Ö. and Anğın, A.D. and Çıkman, M. and Pirimoğlu, Z. (2019) ‘HPV TİP 16 VE 18 DIŞINDA POZİTİF, SMEAR SONUCU NORMAL HASTALARIN KOLPOSKOPİK İNCELENMESİ’, İstanbul Tıp Fakültesi Dergisi, 82(4), pp. 212-218. https://doi.org/10.26650/IUITFD.2018.0026 (25 Apr. 2025).


MLA

Denizli, Ramazan, and Önder Sakin and Ali Doğukan Anğın and Muzaffer Seyhan Çıkman and Zehra Meltem Pirimoğlu. HPV TİP 16 VE 18 DIŞINDA POZİTİF, SMEAR SONUCU NORMAL HASTALARIN KOLPOSKOPİK İNCELENMESİ.” İstanbul Tıp Fakültesi Dergisi, vol. 82, no. 4, 2019, pp. 212-218. [Database Container], https://doi.org/10.26650/IUITFD.2018.0026


Vancouver

Denizli R, Sakin Ö, Anğın AD, Çıkman M, Pirimoğlu Z. HPV TİP 16 VE 18 DIŞINDA POZİTİF, SMEAR SONUCU NORMAL HASTALARIN KOLPOSKOPİK İNCELENMESİ. İstanbul Tıp Fakültesi Dergisi [Internet]. 25 Apr. 2025 [cited 25 Apr. 2025];82(4):212-218. Available from: https://doi.org/10.26650/IUITFD.2018.0026 doi: 10.26650/IUITFD.2018.0026


ISNAD

Denizli, Ramazan - Sakin, Önder - Anğın, AliDoğukan - Çıkman, Muzaffer Seyhan - Pirimoğlu, Zehra Meltem. HPV TİP 16 VE 18 DIŞINDA POZİTİF, SMEAR SONUCU NORMAL HASTALARIN KOLPOSKOPİK İNCELENMESİ”. İstanbul Tıp Fakültesi Dergisi 82/4 (Apr. 2025): 212-218. https://doi.org/10.26650/IUITFD.2018.0026



ZAMAN ÇİZELGESİ


Gönderim19.11.2018
Kabul26.03.2019
Çevrimiçi Yayınlanma19.07.2019

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