Research Article

DOI :10.26650/eor.2021858837   IUP :10.26650/eor.2021858837    Full Text (PDF)

The effects of Biofreeze and superficial heat on masticatory myofascial pain syndrome

Deniz YamanCansu AlpaslanOya Kalaycıoğlu

Purpose: This study aims to assess the influence of superficial heat and Biofreeze on pain, mouth opening (mm), and quality of life in patients with masticatory myofascial pain syndrome (MPS). Subjects and methods: 52 patients with MPS were included in the study. They were randomly divided into two groups. Patients in the Biofreeze group (n = 26) applied 3.5% menthol gel to the masseter and temporal muscles twice a day for seven days, while the other group applied superficial heat. Baseline, 7th, and 21st days of VAS, mouth opening (mm), and Oral Health Impact Profile-14 (OHIP-14) scores of the patients were evaluated statistically. Results: The mouth opening increased by 4.27 ± 3.80 mm in the Biofreeze group and 2.58 ± 2.16 mm in the superficial heat group. In each group, a significant decrease in VAS and OHIP14 scores was observed on the 7th day compared to the baseline values (p<0.001). There was no statistically significant difference between the two applications on myofascial pain, mouth opening (mm), and OHIP-14 total score variables. The favorable effects of both applications on these parameters were limited to the duration of use. Conclusion: Biofreeze and superficial heat in MPS were found to increase the quality of life, but the limited effectiveness of these applications underlines the importance of the underlying factors.

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Yaman, D., Alpaslan, C., & Kalaycıoğlu, O. (2019). The effects of Biofreeze and superficial heat on masticatory myofascial pain syndrome. European Oral Research, 0(0), -.


Yaman D, Alpaslan C, Kalaycıoğlu O. The effects of Biofreeze and superficial heat on masticatory myofascial pain syndrome. European Oral Research. 2019;0(0):-.


Yaman, D.; Alpaslan, C.; Kalaycıoğlu, O. The effects of Biofreeze and superficial heat on masticatory myofascial pain syndrome. European Oral Research, [Publisher Location], v. 0, n. 0, p. -, 2019.

Chicago: Author-Date Style

Yaman, Deniz, and Cansu Alpaslan and Oya Kalaycıoğlu. 2019. “The effects of Biofreeze and superficial heat on masticatory myofascial pain syndrome.” European Oral Research 0, no. 0: -.

Chicago: Humanities Style

Yaman, Deniz, and Cansu Alpaslan and Oya Kalaycıoğlu. The effects of Biofreeze and superficial heat on masticatory myofascial pain syndrome.” European Oral Research 0, no. 0 (Jun. 2021): -.

Harvard: Australian Style

Yaman, D & Alpaslan, C & Kalaycıoğlu, O 2019, 'The effects of Biofreeze and superficial heat on masticatory myofascial pain syndrome', European Oral Research, vol. 0, no. 0, pp. -, viewed 23 Jun. 2021,

Harvard: Author-Date Style

Yaman, D. and Alpaslan, C. and Kalaycıoğlu, O. (2019) ‘The effects of Biofreeze and superficial heat on masticatory myofascial pain syndrome’, European Oral Research, 0(0), pp. -. (23 Jun. 2021).


Yaman, Deniz, and Cansu Alpaslan and Oya Kalaycıoğlu. The effects of Biofreeze and superficial heat on masticatory myofascial pain syndrome.” European Oral Research, vol. 0, no. 0, 2019, pp. -. [Database Container],


Yaman D, Alpaslan C, Kalaycıoğlu O. The effects of Biofreeze and superficial heat on masticatory myofascial pain syndrome. European Oral Research [Internet]. 23 Jun. 2021 [cited 23 Jun. 2021];0(0):-. Available from: doi: 10.26650/eor.2021858837


Yaman, Deniz - Alpaslan, Cansu - Kalaycıoğlu, Oya. The effects of Biofreeze and superficial heat on masticatory myofascial pain syndrome”. European Oral Research 0/0 (Jun. 2021): -.




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