Research Article


DOI :10.26650/IstanbulJPharm.2020.0090   IUP :10.26650/IstanbulJPharm.2020.0090    Full Text (PDF)

Pseudo ternary phase diagrams: a practical approach for the area and centroid calculation of stable microemulsion regions

Murat Sami BerkmanKadri Güleç

Background and Aims: This study aims to develop and evaluate a practical approach for the complicated area and centroid calculation of stable microemulsion regions. Pseudo ternary phase diagrams are used to determine the region of microemulsion existence. The effect of various surfactant/co-surfactant weight ratios on the extent of a stable microemulsion area can easily be observed with these diagrams. Furthermore, the optimum formulations are selected using the centroid of the microemulsion region. Methods: Microemulsion formulations were prepared by changing the weight ratios of the components. The titration method was used at a constant temperature. A pseudo ternary phase diagram was constructed using the spots of the stable microemulsion formulations. Results: The area and centroid of the stable microemulsion region were calculated by using the formulas manually and the macro edited for Microsoft® Excel. Both results were the same. The macro was user-friendly, easy to use, and worked well in Microsoft® Excel. Conclusion: Definitions, formulas, algorithms, and calculations used in this research will be constructive for everyone interested in this field and can be modified very easily in every different case.


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APA

Berkman, M.S., & Güleç, K. (2021). Pseudo ternary phase diagrams: a practical approach for the area and centroid calculation of stable microemulsion regions. İstanbul Journal of Pharmacy, 51(1), 42-49. https://doi.org/10.26650/IstanbulJPharm.2020.0090


AMA

Berkman M S, Güleç K. Pseudo ternary phase diagrams: a practical approach for the area and centroid calculation of stable microemulsion regions. İstanbul Journal of Pharmacy. 2021;51(1):42-49. https://doi.org/10.26650/IstanbulJPharm.2020.0090


ABNT

Berkman, M.S.; Güleç, K. Pseudo ternary phase diagrams: a practical approach for the area and centroid calculation of stable microemulsion regions. İstanbul Journal of Pharmacy, [Publisher Location], v. 51, n. 1, p. 42-49, 2021.


Chicago: Author-Date Style

Berkman, Murat Sami, and Kadri Güleç. 2021. “Pseudo ternary phase diagrams: a practical approach for the area and centroid calculation of stable microemulsion regions.” İstanbul Journal of Pharmacy 51, no. 1: 42-49. https://doi.org/10.26650/IstanbulJPharm.2020.0090


Chicago: Humanities Style

Berkman, Murat Sami, and Kadri Güleç. Pseudo ternary phase diagrams: a practical approach for the area and centroid calculation of stable microemulsion regions.” İstanbul Journal of Pharmacy 51, no. 1 (Jun. 2021): 42-49. https://doi.org/10.26650/IstanbulJPharm.2020.0090


Harvard: Australian Style

Berkman, MS & Güleç, K 2021, 'Pseudo ternary phase diagrams: a practical approach for the area and centroid calculation of stable microemulsion regions', İstanbul Journal of Pharmacy, vol. 51, no. 1, pp. 42-49, viewed 23 Jun. 2021, https://doi.org/10.26650/IstanbulJPharm.2020.0090


Harvard: Author-Date Style

Berkman, M.S. and Güleç, K. (2021) ‘Pseudo ternary phase diagrams: a practical approach for the area and centroid calculation of stable microemulsion regions’, İstanbul Journal of Pharmacy, 51(1), pp. 42-49. https://doi.org/10.26650/IstanbulJPharm.2020.0090 (23 Jun. 2021).


MLA

Berkman, Murat Sami, and Kadri Güleç. Pseudo ternary phase diagrams: a practical approach for the area and centroid calculation of stable microemulsion regions.” İstanbul Journal of Pharmacy, vol. 51, no. 1, 2021, pp. 42-49. [Database Container], https://doi.org/10.26650/IstanbulJPharm.2020.0090


Vancouver

Berkman MS, Güleç K. Pseudo ternary phase diagrams: a practical approach for the area and centroid calculation of stable microemulsion regions. İstanbul Journal of Pharmacy [Internet]. 23 Jun. 2021 [cited 23 Jun. 2021];51(1):42-49. Available from: https://doi.org/10.26650/IstanbulJPharm.2020.0090 doi: 10.26650/IstanbulJPharm.2020.0090


ISNAD

Berkman, MuratSami - Güleç, Kadri. Pseudo ternary phase diagrams: a practical approach for the area and centroid calculation of stable microemulsion regions”. İstanbul Journal of Pharmacy 51/1 (Jun. 2021): 42-49. https://doi.org/10.26650/IstanbulJPharm.2020.0090



TIMELINE


Submitted17.09.2020
Accepted10.12.2020
Published Online30.04.2021

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