Meeting Abstract


DOI :10.26650/JARHS2021-1145612   IUP :10.26650/JARHS2021-1145612    Full Text (PDF)

INVESTIGATION OF THE EFFECT PISTACIA VERA FROM DIFFERENT REGIONS ON OXIDATIVE STRESS AND PROLIFERATION IN BREAST CANCER CELL LINE

İpek GürkebabçıBaşak KoçdorHilal Koçdor

Objective: To investigate the effectiveness of extracts obtained from the inner shell of P. vera plants collected from different regions Materials and Methods: Flavanol and methanol extracts were prepared from the inner shell of P. vera. The cytotoxic effects of the prepared extracts on invasive breast cancer cell lines were determined by our modified MTT cytotoxicity test. Total antioxidant and total oxidant tests were applied, and oxidative stress indices were examined. Migration test was used to investigate the effects of the agents used on the motility of the cells, and colony formation assay was performed to investigate the effect on the colony forming feature. Results: P. vera methanol extracts were found to be more cytotoxic than flavanol extracts. Siirt P. vera Methanol extract was found to be the most cytotoxic extract. P. vera Urfa dissolved in methanol extract due to has high oxidative stress was the most effective in reducing migration in MDA-MB-231 cell line among the groups. Conclusions: Urfa P. vera Methanol extract is most effective in invasive breast cancer cells due to high oxidative stress level that occurs.


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    APA

    Gürkebabçı, İ., Koçdor, B., & Koçdor, H. (2022). INVESTIGATION OF THE EFFECT PISTACIA VERA FROM DIFFERENT REGIONS ON OXIDATIVE STRESS AND PROLIFERATION IN BREAST CANCER CELL LINE. Journal of Advanced Research in Health Sciences, 5(1), 59-59. https://doi.org/10.26650/JARHS2021-1145612


    AMA

    Gürkebabçı İ, Koçdor B, Koçdor H. INVESTIGATION OF THE EFFECT PISTACIA VERA FROM DIFFERENT REGIONS ON OXIDATIVE STRESS AND PROLIFERATION IN BREAST CANCER CELL LINE. Journal of Advanced Research in Health Sciences. 2022;5(1):59-59. https://doi.org/10.26650/JARHS2021-1145612


    ABNT

    Gürkebabçı, İ.; Koçdor, B.; Koçdor, H. INVESTIGATION OF THE EFFECT PISTACIA VERA FROM DIFFERENT REGIONS ON OXIDATIVE STRESS AND PROLIFERATION IN BREAST CANCER CELL LINE. Journal of Advanced Research in Health Sciences, [Publisher Location], v. 5, n. 1, p. 59-59, 2022.


    Chicago: Author-Date Style

    Gürkebabçı, İpek, and Başak Koçdor and Hilal Koçdor. 2022. “INVESTIGATION OF THE EFFECT PISTACIA VERA FROM DIFFERENT REGIONS ON OXIDATIVE STRESS AND PROLIFERATION IN BREAST CANCER CELL LINE.” Journal of Advanced Research in Health Sciences 5, no. 1: 59-59. https://doi.org/10.26650/JARHS2021-1145612


    Chicago: Humanities Style

    Gürkebabçı, İpek, and Başak Koçdor and Hilal Koçdor. INVESTIGATION OF THE EFFECT PISTACIA VERA FROM DIFFERENT REGIONS ON OXIDATIVE STRESS AND PROLIFERATION IN BREAST CANCER CELL LINE.” Journal of Advanced Research in Health Sciences 5, no. 1 (Feb. 2024): 59-59. https://doi.org/10.26650/JARHS2021-1145612


    Harvard: Australian Style

    Gürkebabçı, İ & Koçdor, B & Koçdor, H 2022, 'INVESTIGATION OF THE EFFECT PISTACIA VERA FROM DIFFERENT REGIONS ON OXIDATIVE STRESS AND PROLIFERATION IN BREAST CANCER CELL LINE', Journal of Advanced Research in Health Sciences, vol. 5, no. 1, pp. 59-59, viewed 24 Feb. 2024, https://doi.org/10.26650/JARHS2021-1145612


    Harvard: Author-Date Style

    Gürkebabçı, İ. and Koçdor, B. and Koçdor, H. (2022) ‘INVESTIGATION OF THE EFFECT PISTACIA VERA FROM DIFFERENT REGIONS ON OXIDATIVE STRESS AND PROLIFERATION IN BREAST CANCER CELL LINE’, Journal of Advanced Research in Health Sciences, 5(1), pp. 59-59. https://doi.org/10.26650/JARHS2021-1145612 (24 Feb. 2024).


    MLA

    Gürkebabçı, İpek, and Başak Koçdor and Hilal Koçdor. INVESTIGATION OF THE EFFECT PISTACIA VERA FROM DIFFERENT REGIONS ON OXIDATIVE STRESS AND PROLIFERATION IN BREAST CANCER CELL LINE.” Journal of Advanced Research in Health Sciences, vol. 5, no. 1, 2022, pp. 59-59. [Database Container], https://doi.org/10.26650/JARHS2021-1145612


    Vancouver

    Gürkebabçı İ, Koçdor B, Koçdor H. INVESTIGATION OF THE EFFECT PISTACIA VERA FROM DIFFERENT REGIONS ON OXIDATIVE STRESS AND PROLIFERATION IN BREAST CANCER CELL LINE. Journal of Advanced Research in Health Sciences [Internet]. 24 Feb. 2024 [cited 24 Feb. 2024];5(1):59-59. Available from: https://doi.org/10.26650/JARHS2021-1145612 doi: 10.26650/JARHS2021-1145612


    ISNAD

    Gürkebabçı, İpek - Koçdor, Başak - Koçdor, Hilal. INVESTIGATION OF THE EFFECT PISTACIA VERA FROM DIFFERENT REGIONS ON OXIDATIVE STRESS AND PROLIFERATION IN BREAST CANCER CELL LINE”. Journal of Advanced Research in Health Sciences 5/1 (Feb. 2024): 59-59. https://doi.org/10.26650/JARHS2021-1145612



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    Published Online09.08.2022

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