Meeting Abstract


DOI :10.26650/JARHS2021-1138055   IUP :10.26650/JARHS2021-1138055    Full Text (PDF)

INVESTIGATION OF THE EXPRESSION LEVEL OF miR 142-3P IN OVARIAN CARCINOMA

Yasemin GiderXhariqa JabbarlıGamze UyaroğluDemet Akdeniz ÖdemişŞeref Buğra TunçerBüşra KurtSeda Kılıç ErciyasÖzge Şükrüoğlu ErdoğanBetül ÇelikHülya Yazıcı

Objective: The most common cancers in women are breast, thyroid, colorectal, uterine corpus, lung and ovarian cancer. Ovarian cancer causes more than 150,000 deaths annually worldwide. The fact that this cancer manifests itself in the late stage and is a disease characterized by poor prognosis causes the vast majority of cases to result in death.The target of diagnosis and treatment of ovarian cancer is to reduce the number of deaths and to increase the quality of life.miRNAs play a role in the pathology of many diseases, including cancer. Materials and Methods: In the preliminary study on miRNA in our group, 99 candidate miRNAs were found to be used in the diagnosis and followup of ovarian cancer. In the presented thesis study, the expression level of miR-142-3p among these miRNAs was examined comparatively with a larger ovarian cancer patient group and control group. In the study, which includes 147 patients and 100 healthy control groups, the expression level of miR-142-3p was determined using the RealTime PCR method. Differences between the expression levels of miR-142-3p detected in peripheral blood lymphocytes of ovarian cancer patients and healthy controls were statistically evaluated. Result: It was found that miR-142-3p expression level increased more than 3 times in ovarian cancer patients compared to healthy controls, and this difference was found to be statistically significant (p = 0.00). Conclusion: As a result suggest that miR-142-3p may be a sensitive, non-invasive biomarker in the early diagnosis of ovarian cancer, but further research is needed to investigate and evaluate the related molecule in ovarian benign diseases.


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    APA

    Gider, Y., Jabbarlı, X., Uyaroğlu, G., Akdeniz Ödemiş, D., Tunçer, Ş.B., Kurt, B., Kılıç Erciyas, S., Şükrüoğlu Erdoğan, Ö., Çelik, B., & Yazıcı, H. (2022). INVESTIGATION OF THE EXPRESSION LEVEL OF miR 142-3P IN OVARIAN CARCINOMA. Journal of Advanced Research in Health Sciences, 5(1), 38-38. https://doi.org/10.26650/JARHS2021-1138055


    AMA

    Gider Y, Jabbarlı X, Uyaroğlu G, Akdeniz Ödemiş D, Tunçer Ş B, Kurt B, Kılıç Erciyas S, Şükrüoğlu Erdoğan Ö, Çelik B, Yazıcı H. INVESTIGATION OF THE EXPRESSION LEVEL OF miR 142-3P IN OVARIAN CARCINOMA. Journal of Advanced Research in Health Sciences. 2022;5(1):38-38. https://doi.org/10.26650/JARHS2021-1138055


    ABNT

    Gider, Y.; Jabbarlı, X.; Uyaroğlu, G.; Akdeniz Ödemiş, D.; Tunçer, Ş.B.; Kurt, B.; Kılıç Erciyas, S.; Şükrüoğlu Erdoğan, Ö.; Çelik, B.; Yazıcı, H. INVESTIGATION OF THE EXPRESSION LEVEL OF miR 142-3P IN OVARIAN CARCINOMA. Journal of Advanced Research in Health Sciences, [Publisher Location], v. 5, n. 1, p. 38-38, 2022.


    Chicago: Author-Date Style

    Gider, Yasemin, and Xhariqa Jabbarlı and Gamze Uyaroğlu and Demet Akdeniz Ödemiş and Şeref Buğra Tunçer and Büşra Kurt and Seda Kılıç Erciyas and Özge Şükrüoğlu Erdoğan and Betül Çelik and Hülya Yazıcı. 2022. “INVESTIGATION OF THE EXPRESSION LEVEL OF miR 142-3P IN OVARIAN CARCINOMA.” Journal of Advanced Research in Health Sciences 5, no. 1: 38-38. https://doi.org/10.26650/JARHS2021-1138055


    Chicago: Humanities Style

    Gider, Yasemin, and Xhariqa Jabbarlı and Gamze Uyaroğlu and Demet Akdeniz Ödemiş and Şeref Buğra Tunçer and Büşra Kurt and Seda Kılıç Erciyas and Özge Şükrüoğlu Erdoğan and Betül Çelik and Hülya Yazıcı. INVESTIGATION OF THE EXPRESSION LEVEL OF miR 142-3P IN OVARIAN CARCINOMA.” Journal of Advanced Research in Health Sciences 5, no. 1 (Feb. 2024): 38-38. https://doi.org/10.26650/JARHS2021-1138055


    Harvard: Australian Style

    Gider, Y & Jabbarlı, X & Uyaroğlu, G & Akdeniz Ödemiş, D & Tunçer, ŞB & Kurt, B & Kılıç Erciyas, S & Şükrüoğlu Erdoğan, Ö & Çelik, B & Yazıcı, H 2022, 'INVESTIGATION OF THE EXPRESSION LEVEL OF miR 142-3P IN OVARIAN CARCINOMA', Journal of Advanced Research in Health Sciences, vol. 5, no. 1, pp. 38-38, viewed 24 Feb. 2024, https://doi.org/10.26650/JARHS2021-1138055


    Harvard: Author-Date Style

    Gider, Y. and Jabbarlı, X. and Uyaroğlu, G. and Akdeniz Ödemiş, D. and Tunçer, Ş.B. and Kurt, B. and Kılıç Erciyas, S. and Şükrüoğlu Erdoğan, Ö. and Çelik, B. and Yazıcı, H. (2022) ‘INVESTIGATION OF THE EXPRESSION LEVEL OF miR 142-3P IN OVARIAN CARCINOMA’, Journal of Advanced Research in Health Sciences, 5(1), pp. 38-38. https://doi.org/10.26650/JARHS2021-1138055 (24 Feb. 2024).


    MLA

    Gider, Yasemin, and Xhariqa Jabbarlı and Gamze Uyaroğlu and Demet Akdeniz Ödemiş and Şeref Buğra Tunçer and Büşra Kurt and Seda Kılıç Erciyas and Özge Şükrüoğlu Erdoğan and Betül Çelik and Hülya Yazıcı. INVESTIGATION OF THE EXPRESSION LEVEL OF miR 142-3P IN OVARIAN CARCINOMA.” Journal of Advanced Research in Health Sciences, vol. 5, no. 1, 2022, pp. 38-38. [Database Container], https://doi.org/10.26650/JARHS2021-1138055


    Vancouver

    Gider Y, Jabbarlı X, Uyaroğlu G, Akdeniz Ödemiş D, Tunçer ŞB, Kurt B, Kılıç Erciyas S, Şükrüoğlu Erdoğan Ö, Çelik B, Yazıcı H. INVESTIGATION OF THE EXPRESSION LEVEL OF miR 142-3P IN OVARIAN CARCINOMA. Journal of Advanced Research in Health Sciences [Internet]. 24 Feb. 2024 [cited 24 Feb. 2024];5(1):38-38. Available from: https://doi.org/10.26650/JARHS2021-1138055 doi: 10.26650/JARHS2021-1138055


    ISNAD

    Gider, Yasemin - Jabbarlı, Xhariqa - Uyaroğlu, Gamze - Akdeniz Ödemiş, Demet - Tunçer, ŞerefBuğra - Kurt, Büşra - Kılıç Erciyas, Seda - Şükrüoğlu Erdoğan, Özge - Çelik, Betül - Yazıcı, Hülya. INVESTIGATION OF THE EXPRESSION LEVEL OF miR 142-3P IN OVARIAN CARCINOMA”. Journal of Advanced Research in Health Sciences 5/1 (Feb. 2024): 38-38. https://doi.org/10.26650/JARHS2021-1138055



    TIMELINE


    Published Online09.08.2022

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