Research Article


DOI :10.26650/IUITFD.1175498   IUP :10.26650/IUITFD.1175498    Full Text (PDF)

REGIONAL INVOLVEMENT IN LEFT VENTRICULAR STRAIN IN PATIENTS RECOVERED FROM COVID-19 PNEUMONIA

Ekrem Bilal KaraayvazBerat EnginPelin Karaca ÖzerZeynep Gizem DemirtakanElif Ayduk GövdeliTürker DemirtakanDerya BaykızAlpay Medetalibeyoğlu

Objective: COVID-19 patients with cardiovascular involvement have been shown to have a worse prognosis compared to those without cardiovascular compromise. This study aimed to investigate whether left ventricular (LV) global and regional strain is impaired in patients with COVID-19 with or without pneumonia after discharge. Materials and Methods: Seventy-eight consecutive COVID-19 patients diagnosed by PCR test were enrolled in this cross-sectional study during their first follow-up visit to an outpatient clinic. All patients underwent two-dimensional echocardiography and speckle tracking echocardiography (STE) at the first follow-up visit. The patients were divided into two groups with or without pneumonia, and they were compared with the healthy control group. Results: A total of 123 subjects were included in the study (78 with COVID-19 and 45 in the control group). Admission and follow-up hs-troponin-T concentrations were similar in both the control group and patients with varying severity of COVID-19. LV ejection fraction (EF) was similar in all groups. However, LV global longitudinal strain (GLS) was significantly lower in subjects with pneumonia compared to the control group and subjects without pneumonia. Regional strain analysis showed that subjects with pneumonia had significantly lower strain values at mid-anterior, mid-anteroseptal, apical-inferior, apical-lateral, and apex regions than subjects without pneumonia or the control group. Conclusion: LV GLS and the regional strain were significantly impaired in COVID-19 patients with pneumonia compared to those without pneumonia or in to control group. This finding indicates that COVID-19 subjects with pneumonia should undergo strain measurement to detect concealed LV involvement.

DOI :10.26650/IUITFD.1175498   IUP :10.26650/IUITFD.1175498    Full Text (PDF)

COVID-19 PNÖMONİSİ GEÇİRMİŞ HASTALARDA SOL VENTRİKÜL STRAİN DEĞERİNİN BÖLGESEL TUTULUMU

Ekrem Bilal KaraayvazBerat EnginPelin Karaca ÖzerZeynep Gizem DemirtakanElif Ayduk GövdeliTürker DemirtakanDerya BaykızAlpay Medetalibeyoğlu

Amaç: Kardiyovasküler tutulumu olan COVID-19 hastalarının, kardiyovasküler tutulumu olmayanlara göre daha kötü prognoza sahip olduğu gösterilmiştir. Bu çalışma, pnömonisi olan ve olmayan COVID-19 hastalarında taburculuk sonrası sol ventrikül (LV) global ve bölgesel strain değerinin bozulup bozulmadığını araştırmaktadır. Gereç ve Yöntem: Bu kesitsel çalışmaya, PCR testi ile tanı konulan ve polikliniğimize başvuran 78 hasta dahil edildi. Tüm hastalara ilk muayenelerinde iki boyutlu ekokardiyografi ve speckle tracking ekokardiyografi (STE) yapıldı. Hastalar pnömonisi olan ve olmayan olarak iki gruba ayrıldı ve sağlıklı kontrol grubu ile karşılaştırıldı. Bulgular: Çalışmaya toplam 123 kişi alındı (78 COVID-19 hastası, 45 sağlıklı kontrol). Hem kontrol grubunda hem de farklı ciddiyetteki COVID-19 hastalarında ilk ve takip hs-troponin-T değerleri benzerdi. Sol ventrikül ejeksiyon fraksiyonu (EF) tüm gruplarda benzerdi. Bununla birlikte, sağlıklı kontroller ve pnömonisi olmayan hastalara kıyasla pnömonisi olan hastalarda LV global longitudinal straini (GLS) anlamlı ölçüde daha düşüktü. Bölgesel strain analizi, pnömonisi olmayan hastalara ve kontrol grubuna kıyasla pnömonisi olan hastaların mid-anterior, mid-anteroseptal, apikal-inferior, apikal-lateral and apeks bölgelerinde önemli ölçüde daha düşük strain değerlerine sahip olduğunu göstermiştir. Sonuç: Pnömonisi olmayan hastalara ve sağlıklı kontrollere kıyasla pnömonisi olan COVID-19 hastalarında Sol ventrikül global ve bölgesel strain önemli ölçüde bozulmuştur. Bu bulgu, pnömonisi olan COVID-19 hastalarının, gizli sol ventrikül tutulumunun tespiti için strain ekokardiyografi ile değerlendirilmesi gerektiğini göstermektedir.


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APA

Karaayvaz, E.B., Engin, B., Karaca Özer, P., Demirtakan, Z.G., Ayduk Gövdeli, E., Demirtakan, T., Baykız, D., & Medetalibeyoğlu, A. (2023). REGIONAL INVOLVEMENT IN LEFT VENTRICULAR STRAIN IN PATIENTS RECOVERED FROM COVID-19 PNEUMONIA. Journal of Istanbul Faculty of Medicine, 86(1), 7-13. https://doi.org/10.26650/IUITFD.1175498


AMA

Karaayvaz E B, Engin B, Karaca Özer P, Demirtakan Z G, Ayduk Gövdeli E, Demirtakan T, Baykız D, Medetalibeyoğlu A. REGIONAL INVOLVEMENT IN LEFT VENTRICULAR STRAIN IN PATIENTS RECOVERED FROM COVID-19 PNEUMONIA. Journal of Istanbul Faculty of Medicine. 2023;86(1):7-13. https://doi.org/10.26650/IUITFD.1175498


ABNT

Karaayvaz, E.B.; Engin, B.; Karaca Özer, P.; Demirtakan, Z.G.; Ayduk Gövdeli, E.; Demirtakan, T.; Baykız, D.; Medetalibeyoğlu, A. REGIONAL INVOLVEMENT IN LEFT VENTRICULAR STRAIN IN PATIENTS RECOVERED FROM COVID-19 PNEUMONIA. Journal of Istanbul Faculty of Medicine, [Publisher Location], v. 86, n. 1, p. 7-13, 2023.


Chicago: Author-Date Style

Karaayvaz, Ekrem Bilal, and Berat Engin and Pelin Karaca Özer and Zeynep Gizem Demirtakan and Elif Ayduk Gövdeli and Türker Demirtakan and Derya Baykız and Alpay Medetalibeyoğlu. 2023. “REGIONAL INVOLVEMENT IN LEFT VENTRICULAR STRAIN IN PATIENTS RECOVERED FROM COVID-19 PNEUMONIA.” Journal of Istanbul Faculty of Medicine 86, no. 1: 7-13. https://doi.org/10.26650/IUITFD.1175498


Chicago: Humanities Style

Karaayvaz, Ekrem Bilal, and Berat Engin and Pelin Karaca Özer and Zeynep Gizem Demirtakan and Elif Ayduk Gövdeli and Türker Demirtakan and Derya Baykız and Alpay Medetalibeyoğlu. REGIONAL INVOLVEMENT IN LEFT VENTRICULAR STRAIN IN PATIENTS RECOVERED FROM COVID-19 PNEUMONIA.” Journal of Istanbul Faculty of Medicine 86, no. 1 (Mar. 2024): 7-13. https://doi.org/10.26650/IUITFD.1175498


Harvard: Australian Style

Karaayvaz, EB & Engin, B & Karaca Özer, P & Demirtakan, ZG & Ayduk Gövdeli, E & Demirtakan, T & Baykız, D & Medetalibeyoğlu, A 2023, 'REGIONAL INVOLVEMENT IN LEFT VENTRICULAR STRAIN IN PATIENTS RECOVERED FROM COVID-19 PNEUMONIA', Journal of Istanbul Faculty of Medicine, vol. 86, no. 1, pp. 7-13, viewed 2 Mar. 2024, https://doi.org/10.26650/IUITFD.1175498


Harvard: Author-Date Style

Karaayvaz, E.B. and Engin, B. and Karaca Özer, P. and Demirtakan, Z.G. and Ayduk Gövdeli, E. and Demirtakan, T. and Baykız, D. and Medetalibeyoğlu, A. (2023) ‘REGIONAL INVOLVEMENT IN LEFT VENTRICULAR STRAIN IN PATIENTS RECOVERED FROM COVID-19 PNEUMONIA’, Journal of Istanbul Faculty of Medicine, 86(1), pp. 7-13. https://doi.org/10.26650/IUITFD.1175498 (2 Mar. 2024).


MLA

Karaayvaz, Ekrem Bilal, and Berat Engin and Pelin Karaca Özer and Zeynep Gizem Demirtakan and Elif Ayduk Gövdeli and Türker Demirtakan and Derya Baykız and Alpay Medetalibeyoğlu. REGIONAL INVOLVEMENT IN LEFT VENTRICULAR STRAIN IN PATIENTS RECOVERED FROM COVID-19 PNEUMONIA.” Journal of Istanbul Faculty of Medicine, vol. 86, no. 1, 2023, pp. 7-13. [Database Container], https://doi.org/10.26650/IUITFD.1175498


Vancouver

Karaayvaz EB, Engin B, Karaca Özer P, Demirtakan ZG, Ayduk Gövdeli E, Demirtakan T, Baykız D, Medetalibeyoğlu A. REGIONAL INVOLVEMENT IN LEFT VENTRICULAR STRAIN IN PATIENTS RECOVERED FROM COVID-19 PNEUMONIA. Journal of Istanbul Faculty of Medicine [Internet]. 2 Mar. 2024 [cited 2 Mar. 2024];86(1):7-13. Available from: https://doi.org/10.26650/IUITFD.1175498 doi: 10.26650/IUITFD.1175498


ISNAD

Karaayvaz, EkremBilal - Engin, Berat - Karaca Özer, Pelin - Demirtakan, ZeynepGizem - Ayduk Gövdeli, Elif - Demirtakan, Türker - Baykız, Derya - Medetalibeyoğlu, Alpay. REGIONAL INVOLVEMENT IN LEFT VENTRICULAR STRAIN IN PATIENTS RECOVERED FROM COVID-19 PNEUMONIA”. Journal of Istanbul Faculty of Medicine 86/1 (Mar. 2024): 7-13. https://doi.org/10.26650/IUITFD.1175498



TIMELINE


Submitted14.09.2022
Accepted21.11.2022
Published Online27.01.2023

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