Research Article


DOI :10.26650/IUITFD.1078093   IUP :10.26650/IUITFD.1078093    Full Text (PDF)

ASSOCIATION BETWEEN VITAMIN D AND URIC ACID AMONG NORTH CYPRUS ADULTS: FIRST PRELIMINARY REPORT

Mehtap TınazlıNuriye SancarMeryem GüvenirDeniz Granit Semavi

Objective: The aim of the study is to evaluate the association between serum uric acid (SUA) and 25-OH Vitamin D (25-OH-VIT D). There is no data about the association between hyperuricemia and 25-OH-VIT D deficiency for North Cyprus. Material and Methods: A cross-sectional study was performed on 356 adults aged between 18-75 years in the North Cyprus. Patients socio-demographic information, clinical and biochemical characteristics, eating habits, and lifestyle choices were recorded. Biochemical parameters were evaluated in all patients. Data were analysed by Chi-square test, Student’s t test, and ANOVA, as appropriate. Also, the Gamma correlation coefficient was calculated for the relationship between 25-OH Vitamin D groups and the other variables. Results: The prevalence of 25-OH-VIT D deficiency was 55.9% among the patients (12.86±4.63 ng/mL), the prevalence of 25-OH-VIT D insufficiency (23.44±2.38 ng/mL) was 27%, and 25-OH-VIT D levels were sufficient in only 17.1% of the patients (36.01±5.83 ng/mL). The ANOVA results indicated statistically significant differences SUA for both male and female patients between the 25-OH-VIT D groups. According to the Gamma correlation coefficient values, 25-OH Vitamin D levels were significantly negatively correlated with SUA. Conclusion: In our study indicated a high prevalence of 25-OHVIT D deficiency and insufficiency in North Cyprus adults and we have found a significant association between SUA levels and 25-OH-VIT D. As a result, both vitamin D supplementation and uric acid-lowering therapies are important in protecting patients against future atherosclerotic diseases.

DOI :10.26650/IUITFD.1078093   IUP :10.26650/IUITFD.1078093    Full Text (PDF)

KUZEY KIBRIS YETİŞKİNLERİNDE D VİTAMİNİ VE ÜRİK ASİT ARASINDAKİ İLİŞKİ: BİRİNCİ ÖN HAZIRLIK RAPORU

Mehtap TınazlıNuriye SancarMeryem GüvenirDeniz Granit Semavi

Amaç: Kuzey Kıbrıs için hiperürisemi ile 25-OH-VIT D eksikliği arasındaki ilişki hakkında veri yoktur. Bu çalışmanın amacı serum ürik asit (SUA) ile 25-OH-VIT D arasındaki ilişkiyi değerlendirmektir. Gereç ve Yöntem: Kuzey Kıbrıs’ta yaşları 18-75 arasında değişen 356 yetişkin üzerinde kesitsel bir çalışma yapılmıştır. Hastaların sosyodemografik bilgileri, klinik ve biyokimyasal özellikleri, beslenme alışkanlıkları ve yaşam tarzı tercihleri kaydedildi. Tüm hastalarda biyokimyasal parametreler değerlendirildi. Veriler Ki-kare testi, Student t testi ve uygun şekilde ANOVA ile analiz edildi. Ayrıca 25-OH Vitamin D grupları ile diğer değişkenler arasındaki ilişki için Gama korelasyon katsayısı hesaplandı. Bulgular: Hastalar arasında 25-OH-VIT D eksikliği prevalansı %55,9 (12,86±4,63 ng/mL), 25-OH-VIT D yetmezliği prevalansı (23,44±2,38 ng/mL) %27 idi ve 25-OH-VIT D düzeyleri hastaların sadece %17,1’inde yeterliydi (36,01±5,83 ng/mL). ANOVA sonuçları, 25-OH-VIT D grupları arasında hem erkek hem de kadın hastalar için istatistiksel olarak anlamlı SUA farklılıkları gösterdi. Gama korelasyon katsayısı değerlerine göre, 25-OH Vitamin D düzeyleri SUA ile anlamlı olarak negatif korelasyon gösterdi. Sonuç: Çalışmamızda Kuzey Kıbrıs erişkinlerinde 25-OH-VIT D eksikliği ve yetersizliği prevalansının yüksek olduğu gösterildi ve SUA düzeyleri ile 25-OH-VIT D arasında anlamlı bir ilişki bulundu. Sonuç olarak, hem D vitamini takviyesi hem de ürikasit düşürücü tedaviler, hastaları gelecekteki aterosklerotik hastalıklara karşı korumada önemlidir.


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APA

Tınazlı, M., Sancar, N., Güvenir, M., & Semavi, D.G. (2022). ASSOCIATION BETWEEN VITAMIN D AND URIC ACID AMONG NORTH CYPRUS ADULTS: FIRST PRELIMINARY REPORT. Journal of Istanbul Faculty of Medicine, 85(4), 564-571. https://doi.org/10.26650/IUITFD.1078093


AMA

Tınazlı M, Sancar N, Güvenir M, Semavi D G. ASSOCIATION BETWEEN VITAMIN D AND URIC ACID AMONG NORTH CYPRUS ADULTS: FIRST PRELIMINARY REPORT. Journal of Istanbul Faculty of Medicine. 2022;85(4):564-571. https://doi.org/10.26650/IUITFD.1078093


ABNT

Tınazlı, M.; Sancar, N.; Güvenir, M.; Semavi, D.G. ASSOCIATION BETWEEN VITAMIN D AND URIC ACID AMONG NORTH CYPRUS ADULTS: FIRST PRELIMINARY REPORT. Journal of Istanbul Faculty of Medicine, [Publisher Location], v. 85, n. 4, p. 564-571, 2022.


Chicago: Author-Date Style

Tınazlı, Mehtap, and Nuriye Sancar and Meryem Güvenir and Deniz Granit Semavi. 2022. “ASSOCIATION BETWEEN VITAMIN D AND URIC ACID AMONG NORTH CYPRUS ADULTS: FIRST PRELIMINARY REPORT.” Journal of Istanbul Faculty of Medicine 85, no. 4: 564-571. https://doi.org/10.26650/IUITFD.1078093


Chicago: Humanities Style

Tınazlı, Mehtap, and Nuriye Sancar and Meryem Güvenir and Deniz Granit Semavi. ASSOCIATION BETWEEN VITAMIN D AND URIC ACID AMONG NORTH CYPRUS ADULTS: FIRST PRELIMINARY REPORT.” Journal of Istanbul Faculty of Medicine 85, no. 4 (Nov. 2024): 564-571. https://doi.org/10.26650/IUITFD.1078093


Harvard: Australian Style

Tınazlı, M & Sancar, N & Güvenir, M & Semavi, DG 2022, 'ASSOCIATION BETWEEN VITAMIN D AND URIC ACID AMONG NORTH CYPRUS ADULTS: FIRST PRELIMINARY REPORT', Journal of Istanbul Faculty of Medicine, vol. 85, no. 4, pp. 564-571, viewed 18 Nov. 2024, https://doi.org/10.26650/IUITFD.1078093


Harvard: Author-Date Style

Tınazlı, M. and Sancar, N. and Güvenir, M. and Semavi, D.G. (2022) ‘ASSOCIATION BETWEEN VITAMIN D AND URIC ACID AMONG NORTH CYPRUS ADULTS: FIRST PRELIMINARY REPORT’, Journal of Istanbul Faculty of Medicine, 85(4), pp. 564-571. https://doi.org/10.26650/IUITFD.1078093 (18 Nov. 2024).


MLA

Tınazlı, Mehtap, and Nuriye Sancar and Meryem Güvenir and Deniz Granit Semavi. ASSOCIATION BETWEEN VITAMIN D AND URIC ACID AMONG NORTH CYPRUS ADULTS: FIRST PRELIMINARY REPORT.” Journal of Istanbul Faculty of Medicine, vol. 85, no. 4, 2022, pp. 564-571. [Database Container], https://doi.org/10.26650/IUITFD.1078093


Vancouver

Tınazlı M, Sancar N, Güvenir M, Semavi DG. ASSOCIATION BETWEEN VITAMIN D AND URIC ACID AMONG NORTH CYPRUS ADULTS: FIRST PRELIMINARY REPORT. Journal of Istanbul Faculty of Medicine [Internet]. 18 Nov. 2024 [cited 18 Nov. 2024];85(4):564-571. Available from: https://doi.org/10.26650/IUITFD.1078093 doi: 10.26650/IUITFD.1078093


ISNAD

Tınazlı, Mehtap - Sancar, Nuriye - Güvenir, Meryem - Semavi, DenizGranit. ASSOCIATION BETWEEN VITAMIN D AND URIC ACID AMONG NORTH CYPRUS ADULTS: FIRST PRELIMINARY REPORT”. Journal of Istanbul Faculty of Medicine 85/4 (Nov. 2024): 564-571. https://doi.org/10.26650/IUITFD.1078093



TIMELINE


Submitted24.02.2022
Accepted06.06.2022
Published Online22.07.2022

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