Semantics is a science whose field is words and meanings. It searches for the meanings of words and studies the changes and developments that occur in the meanings of words throughout history. It also searches for the relationship between the signifier and the signified, that is, it searches for the relationship between the letters that are fixed next to each other and what they indicate after they are superimposed. Semantics, when searching for the terms of meanings, adopts the historical approach and the descriptive approach. Interest in semantics and the search for meanings of words began at a very early age, and we find this interest among the early Arab Muslims. For example, commentators and those interested in the sciences of the Qur’an wrote books about the miracle of the Qur’an, the strangeness of the Qur’an, and the Mushkik Al-Qur’an. Fundamentalists used word denotation to express the meanings extracted from the verses and texts, and linguists paid attention to the meanings of words and their derivatives in order to return the words or the meanings of words to a single origin from which many branches come. Thus, we find that the subject of studying the semantics of words among Arabs in the past was confined to these matters, and this subject was not based on one special science with its limitations and rules. Subject of studying the semantics of words did not happen until the end of the nineteenth century at the hands of Western scholars. So, semantics established its rules and laid down its laws, and its field at that time was to search for the meanings of words historically; then, it developed to study the meaning in a specific time and place. This science began to be employed in many fields, such as in an existential understanding of the Qur’an, after studying the meanings of its words. This research analyzes the origin of the q-s-s (ص-ص-ق ) used in the Holy Qur’an historically from the perspective of semantics, to properly understand the meanings of the words derived from this origin and used in the Holy Qur’an, and to identify the derivatives that were derived from it throughout history and the developments that these derivatives have undergone in their meanings. At the beginning, we present an introduction in which we clarify the origins of this science, its topic, and the method of employing this science in understanding the Holy Qur’an, then we explain the historical semantic analysis approach. Then we move on to analyze this root throughout history, from the oldest text that we could access to our current era. Therefore, we clarify and analyze the meanings of the derivatives of the root q-s-s (ص-ص-ق ) in the poetry of the pre-Islamic era by listing the poetic verses that include the derivatives of this root and explaining these verses, and by looking at their context after referring to the books that explain the collections of pre-Islamic poetry. Then we move on to analyzing the meanings of the root derivatives q-s-s (ص-ص-ق ) in the Holy Qur’an by presenting the Quranic verses that include the root derivatives q-s-s (ص-ص-ق (and interpreting these verses after referring to the books of interpretation of the Holy Qur’an that were written between the first and fourth era of the Hijrah. Then we analyze the meanings of the derivatives of the root Q-S-S (Q-S-S) in the poetry of the Islamic era, and we follow in this section the approach that we followed in analyzing the derivatives of the root concerned in the pre-Islamic poetry. In this section, we return to the collections of Islamic poetry that include poetry attributed to the era that followed the revelation of the Holy Qur’an until the codification of ancient Arabic linguistic dictionaries began. Then we move on to the analysis of root derivatives q-s-s (ص-ص-ق ) in the dictionaries of the ancient language and then the dictionaries of the modern language by displaying the meanings of the new derivations of the original q-s-s (ص-ص-ق ) only, without highlighting the meanings that were used in the pre-Islamic era, the era of the revelation of the Qur’an, and the poetry of the Islamic era to avoid repetition. We clarify the relationships between the primary meaning of the q-s-s (ص-ص-ق (root and the meanings of its derivatives during the analysis, to see whether the meaning of the word derived from the root in question is related to the primary semantic domain of the root or not. Knowing this helps us to understand the derivatives of roots in a deep and correct way. At the end of this research, we conclude that this root has a large and wide range of meanings. The use of this root and the derivation of words from it did not end after a specific era. Rather, it continued as needed throughout the ages between the expansion of the use of this root and its derivatives and the narrowing of its use, which indicates its development throughout history and its non-degeneration. We find that a semantic change occurred within some derivatives of the root q-s-s (ص-ص-ق), as if the word denotes one meaning and then denotes another meaning without changing its form or structure. We conclude that all derivatives derived from the root q-s-s (ص-ص-ق )are related to the essential connotation of the root q-s-s (ص-ص-ق), either directly or through interpretation.