Geriatrik Nefroloji

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DOI :10.26650/B/CH12CH47.2023.014.17   IUP :10.26650/B/CH12CH47.2023.014.17    Tam Metin (PDF)

Geri̇atri̇k Popülasyonda Tübüloi̇ntersti̇si̇yel Nefri̇tler Ve Yöneti̇mi̇

Belda Dursun, Murat Yaşar Taş

Tübülointerstisiyel nefritler hem akut hem de kronik böbrek yetmezliğinin sık ve önemli nedenlerindendir.1 Akut tübülointerstisiyel nefrit (ATİN) veya kronik tübülointerstisiyel nefrit (KTİN) tablosuna yol açan birçok neden vardır. Etiyolojide ilaç kullanımı son yıllarda ön plana çıkmaktadır. Tübülointerstisyel nefrit insidansının giderek artmakta olduğu ve özellikle geriatrik bireylerin çoklu ilaç kullanımına (polifarmasi) bağlı olarak yüksek risk altında olduğu dikkat çekmektedir.2 Olguların çoğu kez spesifik-olmayan bulgularla başvurması hastalığın genellikle atlanmasına veya tanıda gecikmelere yol açmaktadır. Erken tanı ile hastalığın farkedilmesi ve kronik böbrek hastalığına (KBH) ilerleyişin engellenmesi özellikle renal rezervin zaten düşük olduğu geriatrik popülasyon açısından çok önemlidir.3 Bu bölümde geriatrik popülasyonda ATİN ilişkili süreçler ön planda tartışılacaktır, KTİN ilişkili durumlara da kısaca değinilecektir.



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