İstanbul Journal of Pharmacy

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DOI :10.26650/IstanbulJPharm.2019.18012   IUP :10.26650/IstanbulJPharm.2019.18012    Tam Metin (PDF)

Qualitative and quantitative phytochemical analysis and in-vitro biological activity of Rheum ribes L. different parts

Turgut Taşkın, Gizem Bulut

The methanol extracts from different parts of Rheum ribes were subjected to qualitative and quantitative phytochemical and in vitro biological activity (antioxidant, anti-urease, anticholinesterase). Qualitative phytochemical tests were performed using standard analysis methods and these studies revealed the presence of phenolics and tannins. Following this, a quantitative determination of total phenolics and tannins contents was carried out. The antioxidant activity of the extracts were assayed using DPPH, FRAP, TEAC/ABTS and CUPRAC techniques. In addition, the anti-urease and anticholinesterase activity of the extracts were examined using indophenol and Ellman methods, respectively. In this study, it was determined that the macerated flowers extract contained higher total phenolic and tannins contents than the other extracts. According to the results obtained from the antioxidant experiment, the macerated extract of flowers showed the strongest ABTS.+ scavenging and ferric reducing antioxidant power activity. The macerated leaves and Soxhlet radix extracts exhibited the strongest DPPH. scavenging and cupric reducing antioxidant activity, respectively. The young shoots extracts obtained using the Soxhlet methods showed the highest anticholinesterase activity. All extracts obtained from different parts of the plant were found to have very low anti-urease activity when compared to the anti-urease activity of standard compound. Therefore, methanol extracts from plant’s flowers, leaves and young shoots can be used as a natural antioxidant and anticholinesterase agent respectively, for the pharmaceutical and food industry in the future.

Anahtar Kelimeler: Rheum ribes, antioxidant, anti-uresae, anticholinesterase, phytochemical analysis

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APA

Taşkın, T., & Bulut, G. (2019). Qualitative and quantitative phytochemical analysis and in-vitro biological activity of Rheum ribes L. different parts. İstanbul Journal of Pharmacy, 49(1), 7-13. https://doi.org/10.26650/IstanbulJPharm.2019.18012


AMA

Taşkın T, Bulut G. Qualitative and quantitative phytochemical analysis and in-vitro biological activity of Rheum ribes L. different parts. İstanbul Journal of Pharmacy. 2019;49(1):7-13. https://doi.org/10.26650/IstanbulJPharm.2019.18012


ABNT

Taşkın, T.; Bulut, G. Qualitative and quantitative phytochemical analysis and in-vitro biological activity of Rheum ribes L. different parts. İstanbul Journal of Pharmacy, [Publisher Location], v. 49, n. 1, p. 7-13, 2019.


Chicago: Author-Date Style

Taşkın, Turgut, and Gizem Bulut. 2019. “Qualitative and quantitative phytochemical analysis and in-vitro biological activity of Rheum ribes L. different parts.” İstanbul Journal of Pharmacy 49, no. 1: 7-13. https://doi.org/10.26650/IstanbulJPharm.2019.18012


Chicago: Humanities Style

Taşkın, Turgut, and Gizem Bulut. “Qualitative and quantitative phytochemical analysis and in-vitro biological activity of Rheum ribes L. different parts.” İstanbul Journal of Pharmacy 49, no. 1 (Jun. 2025): 7-13. https://doi.org/10.26650/IstanbulJPharm.2019.18012


Harvard: Australian Style

Taşkın, T & Bulut, G 2019, 'Qualitative and quantitative phytochemical analysis and in-vitro biological activity of Rheum ribes L. different parts', İstanbul Journal of Pharmacy, vol. 49, no. 1, pp. 7-13, viewed 26 Jun. 2025, https://doi.org/10.26650/IstanbulJPharm.2019.18012


Harvard: Author-Date Style

Taşkın, T. and Bulut, G. (2019) ‘Qualitative and quantitative phytochemical analysis and in-vitro biological activity of Rheum ribes L. different parts’, İstanbul Journal of Pharmacy, 49(1), pp. 7-13. https://doi.org/10.26650/IstanbulJPharm.2019.18012 (26 Jun. 2025).


MLA

Taşkın, Turgut, and Gizem Bulut. “Qualitative and quantitative phytochemical analysis and in-vitro biological activity of Rheum ribes L. different parts.” İstanbul Journal of Pharmacy, vol. 49, no. 1, 2019, pp. 7-13. [Database Container], https://doi.org/10.26650/IstanbulJPharm.2019.18012


Vancouver

Taşkın T, Bulut G. Qualitative and quantitative phytochemical analysis and in-vitro biological activity of Rheum ribes L. different parts. İstanbul Journal of Pharmacy [Internet]. 26 Jun. 2025 [cited 26 Jun. 2025];49(1):7-13. Available from: https://doi.org/10.26650/IstanbulJPharm.2019.18012 doi: 10.26650/IstanbulJPharm.2019.18012


ISNAD

Taşkın, Turgut - Bulut, Gizem. “Qualitative and quantitative phytochemical analysis and in-vitro biological activity of Rheum ribes L. different parts”. İstanbul Journal of Pharmacy 49/1 (Jun. 2025): 7-13. https://doi.org/10.26650/IstanbulJPharm.2019.18012



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Kabul06.03.2019

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