İlke

Yaren

Özge

Hande

Yağmur

In Silico Approach for Identification of PI3K/mTOR Dual  Inhibitors for Multiple Myeloma Treatment

Mahmood

Porang

Hamid

Mohammad

Effects of Salicylic Acid and Microorganisms on Morphological and Physiological Characteristics (Satureja hortensis L.) under Drought Stress

Sanjeda

Rocky

Taslimul

Laila

Evaluation of Oxidative Protein Damage in Patients with Type 1 and 2 Diabetes Mellitus in Bangladesh

Fatma

Çağlar

Güzin

Tuğba

Göksel

Feriha

Morphological and Biochemical Investigation of the Protective Effects of Panax ginseng on Methotrexate-Induced Testicular Damage

Pınar

Tülin

Anti-Bacterial, Anti-Mycobacterial and Anti-Fungal Properties of Punica granatum as Natural Dye

Ertan

Semih

Ferah

Azmi

The Senescence Program is Reduced in Proteasome Inhibitor Bortezomib-Resistant PC3 Prostate Cancer Cell Line

Yüksel

Gülce

Ayşe

Rengin

Morphological and Molecular Identification of Trichoderma Isolates Used as Biocontrol Agents by DNA Barcoding

Saim

Mokrani

Uzman

Isabel

Ramazan

Screening of Antibiotics Biodegradability from Wastewater

Elif

Leila

Ajda

The Use of Plant Steroids in Viral Disease Treatments:  Current Status and Future Perspectives

Akshat

Aahmad

Dharmeshkumar

The Role of Akt Signalling Pathway in Neurological and Cardiovascular Pathologies

Meriem

Ilham

Djamila

Tassadit

Abderrahmane

Impact of Toxic Heavy Metals and Their Concentration in Zygophyllum Species, Mentha longifolia, and Thymus vulgaris Traditional Medicinal Plants Consumed in Setif-Algeria

Şehnaz

Prof.

Call for Paper for the Themed Issue of 2023

Burçin

Ömer

Astragaloside-IV Inhibits Metastasis by Suppressing the SDF-1/CXCR4 Axis and Activating Apoptosis in Cisplatin-Resistant Ovarian Cancer Cells

Seza

Susceptibility of Staphylococcus aureus Isolated from Different Raw Meat Products to Disinfectants

Retrospective Analysis of Transcriptomic Differences between Triple-Negative Breast Cancer (TNBC) and non-TNBC

Ersan

Buket

Suat

Bülent

Investigation of the Relationship between the Multidrug Resistance 1 Gene Polymorphisms and Bronchodilator Response in COPD

Gözde

Sefa

Ayşen

Sevim

In Silico Evaluation of ERQ Bioactive Tripeptide as an Anticancer Agent and an Inhibitor of SARS-CoV-2 Enzymes

Öznur

Aysun

Resveratrol Dose-Dependently Protects the Antioxidant Mechanism of Hydrogen Peroxide-Exposed Healthy Cells and Lung Cancer Cells

Gamze

Ezgi

Abdürrahim

Induction of Apoptosis through Oxidative Stress Caused by Rubus tereticaulis Leaves Extracts in A549 Cells

Serkan

Investigating the Involvement of Fibroblast Growth Factors in Adipose Tissue Thermogenesis

Serdar

Investigating the Antioxidant Capacity of Lunasin Expressed in Aspergillus oryzae

Derya

Merih

Gizem

Semanur

Zülal

İsmail

Selçuk

Ahmet

Ebru

Radiofrequency Electromagnetic Field Exposure Amplifies the Detrimental Effects of Fetal Hyperglycemia in Zebrafish Embryos

Emine

Mukaddes

Birsen

Seda

Changes in Histological Features, Apoptosis and Necroptosis, and Inflammatory Status in the Livers and Kidneys of Young and Adult Rats

Arbab

Hamda

Ravi

Alvina

Archana

Afreen

From Pond Scum to Miracle Molecules: Cyanobacterial Compounds New Frontiers

Bacterial Diversity of the Corpses

Nguyen

Hoang

Induction of Apoptosis in BCR-ABL Fusion Associated Chronic Myeloid Leukemia Cells by Camellia kissiWall. (Theaceae) Extract

@JOURNAL_BOX_CURRENT

Zeynep

Esin

Membrane Damaging and Protective Effects of Gypsophila bicolor’s Grossh. (Caryophyllaceae) Root Extract on H1299, A549, and A431 Cells

Upregulated Acute Systemic Inflammation-Related Genes based on Endotoxin Exposure Provide “Survival Benefit” or Create “High Risk of Death” in Leukaemia and Colon Cancer

Truong

Optimization of Extraction Parameters of Phenolic Compounds from Cau Banana (Musa paradisiaca) Peel and Evaluation for Antioxidant and Antibacterial Potential

Azadeh

Elaheh

Saeed

Effect of the Ethanolic Extract of Eryngium billardieri on the Viability of the Triple-Negative Breast Cancer Cell Line (MDA-MB-231) and CDKN2A, MDM2, and HER2 Expression

Chudamani

Overexpression of Pepper Capsaicinoid Pathway Genes in Tomato (Solanum lycopersicum L.)

@JOURNAL_BOX_EARLYVIEW

Fikriye

Melis

Hasan

Taner

Sinan

Tolga

İnci

Evren

Genetic Diversity of Gazelles (Gazella marica and Gazella gazella) in Southeast Turkey: A Special Emphasis on Ongoing Conservation Studies of Gazella marica in Turkey

Emel

Nilüfer

Hatice

Mahmut

Amaç

Berna

Investigation of Antimicrobial, Antibiofilm, and Cytotoxic Effects of Straight-Chained Sulfanyl Members of Arylamino-1,4-naphthoquinones as Potential Antimicrobial Agents

@JOURNAL_BOX_FEATURED

Sehkar

Ülkü

Determination of Oxidative Stress Parameters and Tissue Factor Activity in the Saliva of Patients with Periodontitis

Nihal

Kevser

Gülay

Filiz

Karrikinolide Promotes Seed Germination but Has no Effect on Leaf Segment Senescence in Triticum aestivum L.

@JOURNAL_BOX_MOSTREAD

European Journal of Biology (Eur J Biol) is an international, scientific, open access periodical published in accordance with independent, unbiased, and double-blinded peer-review principles. The journal is the official publication of Faculty of Science in Istanbul University and it is published biannually on June and December. The publication language of the journal is English. European Journal of Biology has been previously published as IUFS Journal of Biology. It has been published in continuous publication since 1940.

Füsun

Prof. Dr.

CABI

Scopus

EBSCO

Zoological Record

TR Dizin

CAS Source Index

CAB Abstracts

DOAJ

SOBIAD

Cabells Journalytics

@METRIC_VOLUMES

@METRIC_ISSUES

@METRIC_ARTICLES

@METRIC_OPENACCESS

European Journal of Biology

@INFO_TAB_ABOUT

Editor in Chief

Co Editor in Chief

Editorial Management Board Member

Section Editor

Language Editor

Statistics Editor

Ethics Editor

Publicity Manager

Editorial Assistant

Editorial Board Member

@INFO_TAB_BOARDS

European Journal of Biology aims to contribute to the literature by publishing manuscripts at the highest scientific level on all fields of biology. The journal publishes original research and review articles, and short communications that are prepared in accordance with the ethical guidelines in all fields of biology and life sciences.The scope of the journal includes but not limited to; animal  biology and systematics,  plant biology and systematics, hydrobiology, ecology and environmental biology, microbiology, cell and molecular biology, biochemistry, biotechnology and genetics, physiology, toxicology, cancer biology, developmental biology, stem cell biology.

Aim & Scope

Zoological Record - Clarivate AnalyticsCAB Abstracts CABI- AgBiotechNet Database - Animalscience Database- VetMed Resource - Environmental Impact Database - Horticultural Science Database - Nutrition and Food Sciences Database .Chemical Abstracts Service (CAS) ULAKBIM TR IndexScopusDOAJEBSCO Central &amp; Eastern European Academic Source SOBİADCabells Journalytics

Indexing and Abstracting

The journal is committed to upholding the highest standards of publication ethics and pays regard to Principles of Transparency and Best Practice in Scholarly Publishing published by the<a href="https://publicationethics.org/" target="_blank"> Committee on Publication Ethics (COPE)</a>, the <a href="https://doaj.org/apply/transparency/#principles-of-transparency-and-best-practice-in-scholarly-publishing" target="_blank">Directory of Open Access Journals (DOAJ)</a>, the <a href="https://oaspa.org/" target="_blank">Open Access Scholarly Publishers Association (OASPA</a>), and the <a href="http://www.wame.org/" target="_blank">World Association of Medical Editors (WAME)</a> on <a href="https://publicationethics.org/resources/guidelines-new/principles-transparency-and-best-practice-scholarly-publishing" target="_blank">https://publicationethics.org/resources/guidelines-new/principles-transparency-and-best-practice-scholarly-publishing</a> The subjects covered in the manuscripts submitted to the Journal for publication must be in accordance with the aim and scope of the Journal. Only those manuscripts approved by every individual author and that were not published before in or sent to another journal, are accepted for evaluation.Changing the name of an author (omission, addition or order) in papers submitted to the Journal requires written permission of all declared authors.Plagiarism, duplication, fraud authorship/denied authorship, research/data fabrication, salami slicing/salami publication, breaching of copyrights, prevailing conflict of interest are unethical behaviors. All manuscripts not in accordance with the accepted ethical standards will be removed from the publication. This also contains any possible malpractice discovered after the publication. Plagiarism Submitted manuscripts that pass preliminary control are scanned for plagiarism using iThenticate software. If plagiarism/self-plagiarism will be found authors will be informed. Editors may resubmit manuscript for similarity check at any peer-review or production stage if required. High similarity scores may lead to rejection of a manuscript before and even after acceptance. Depending on the type of article and the percentage of similarity score taken from each article, the overall similarity score is generally expected to be less than 15 or 20%. Double Blind Peer-Review After plagiarism check, the eligible ones are evaluated by the editors-in-chief for their originality, methodology, the importance of the subject covered and compliance with the journal scope. The editor provides a fair double-blind peer review of the submitted articles and hands over the papers matching the formal rules to at least two national/international referees for evaluation and gives green light for publication upon modification by the authors in accordance with the referees’ claims.

Policies

The journal is an open access journal and all content is freely available without charge to the user or his/her institution. Except for commercial purposes, users are allowed to read, download, copy, print, search, or link to the full texts of the articles in this journal without asking prior permission from the publisher or the author. This is in accordance with the <a href="https://www.budapestopenaccessinitiative.org/read" target="_blank">BOAI</a> definition of open access.The open access articles in the journal are licensed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International (<a href="https://creativecommons.org/licenses/by-nc/4.0/deed.en" target="_blank">CC BY-NC 4.0</a>) license.

All expenses of the journal are covered by the Istanbul University. Processing and publication are free of charge with the journal. There is no article processing charges or submission fees for any submitted or accepted articles.

Authors publishing with the journal retain the copyright to their work licensed under the Creative Commons Attribution-NonCommercial 4.0 International license (<a href="https://creativecommons.org/licenses/by-nc/4.0/" target="_blank">CC BY-NC 4.0</a>) (<a href="https://creativecommons.org/licenses/by-nc/4.0/" target="_blank">https://creativecommons.org/licenses/by-nc/4.0/</a> ) and grant the Publisher non-exclusive commercial right to publish the work. CC BY-NC 4.0 license permits unrestricted, non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Editor should consider publishing correction if minor errors that do not effect the results, interpretations and conclusions of the published paper are detected. Editor should consider retraction if major errors and/or misconduction that invalidate results and conclusions are detected.Editor should consider issuing an expression of concern if there is evidence of research or publication misconduct by the authors; there is evidence that the findings are not reliable and institutions of the authors do not investigate the case or the possible investigation seems to be unfair or nonconclusive. The guidelines of <a href="https://publicationethics.org/resources/flowcharts/complete-set-english" target="_blank">COPE</a> and <a href="https://www.icmje.org/recommendations/" target="_blank">ICJME </a>are taken into consideration regarding correction, retractions or expression of concern.

To guarantee that all papers published in the journal are maintained and permanently accessible, articles are stored in Dergipark which serves as a  national archival web site and at the same time permits LOCKSS to  collect, preserve, and serve the content.Additionally, authors are encouraged to self-archive the final PDF version of their articles in open electronic archives with  that conform to standards of Open Archives Initiative (<a href="https://www.openarchives.org/" target="_blank">https://www.openarchives.org/</a>). Authors should provide a link from the deposited version to the URL of IUPress journal website.

European Journal of Biology is committed to upholding the highest standards of publication ethics and pays regard to Principles of Transparency and Best Practice in Scholarly Publishing published by the <a href="https://publicationethics.org/" target="_blank">Committee on Publication Ethics (COPE)</a>, the <a href="https://doaj.org/apply/transparency/#principles-of-transparency-and-best-practice-in-scholarly-publishing" target="_blank">Directory of Open Access Journals (DOAJ)</a>, the <a href="https://oaspa.org/" target="_blank">Open Access Scholarly Publishers Association (OASPA)</a>, and the <a href="http://www.wame.org/" target="_blank">World Association of Medical Editors (WAME)</a> on <a href="https://publicationethics.org/resources/guidelines/principles-transparency-and-best-practice-scholarly-publishing" target="_blank">https://publicationethics.org/resources/guidelines/principles-transparency-and-best-practice-scholarly-publishing </a>All parties involved in the publishing process (Editors, Reviewers, Authors and Publishers) are expected to agree on the following ethical principles.All submissions must be original, unpublished (including as full text in conference proceedings), and not under the review of any other publication synchronously. Each manuscript is reviewed by one of the editors and at least two referees under double-blind peer review process. Plagiarism, duplication, fraud authorship/denied authorship, research/data fabrication, salami slicing/salami publication, breaching of copyrights, prevailing conflict of interest are unnethical behaviors.All manuscripts not in accordance with the accepted ethical standards will be removed from the publication. This also contains any possible malpractice discovered after the publication. In accordance with the code of conduct we will report any cases of suspected plagiarism or duplicate publishing.

Ethics

The journal adheres to the highest standards in research ethics and follows the principles of international research ethics as defined below. The authors are responsible for the compliance of the manuscripts with the ethical rules.-    Principles of integrity, quality and transparency should be sustained in designing the research, reviewing the design and conducting the research.-    The research team and participants should be fully informed about the aim, methods, possible uses and requirements of the research and risks of participation in research.-    The confidentiality of the information provided by the research participants and the confidentiality of the respondents should be ensured. The research should be designed to protect the autonomy and dignity of the participants.-    Research participants should participate in the research voluntarily, not under any coercion.-    Any possible harm to participants must be avoided. The research should be planned in such a way that the participants are not at risk.-    The independence of research must be clear; and any conflict of interest or must be disclosed.-    In experimental studies with human subjects, written informed consent of the participants who decide to participate in the research must be obtained. In the case of children and those under wardship or with confirmed insanity, legal custodian’s assent must be obtained.-    If the study is to be carried out in any institution or organization, approval must be obtained from this institution or organization.-    In studies with human subject, it must be noted in the method’s section of the manuscript that the informed consent of the participants and ethics committee approval from the institution where the study has been conducted have been obtained.

The Journal takes as principle to comply with the ethical standards of <a href="https://www.wma.net/policies-post/wma-declaration-of-helsinki-ethical-principles-for-medical-research-involving-human-subjects/" target="_blank">World Medical Association (WMA) Declaration of Helsinki – Ethical Principles for Medical Research Involving Human Subjects</a>,  <a href="https://cdn.istanbul.edu.tr/file/JTA6CLJ8T5/1CA4A5057BC44E33A01111CDB6531BAC" target="_blank">Basel Declaration</a> and <a href="https://www.wma.net/policies-post/wma-statement-on-animal-use-in-biomedical-research/" target="_blank">WMA Statement on Animal Use in Biomedical Research</a>. An approval of research protocols by the Ethics Committee in accordance with international standards mentioned above is required for experimental, clinical, and drug studies and for some case reports. If required, ethics committee reports or an equivalent official document will be requested from the authors. For manuscripts concerning experimental research on humans, a statement should be included that shows that written informed consent of patients and volunteers was obtained following a detailed explanation of the procedures that they may undergo. Information on patient consent, the name of the ethics committee, and the ethics committee approval number should also be stated in the Materials and Methods section of the manuscript. It is the authors’ responsibility to carefully protect the patients’ anonymity. For photographs that may reveal the identity of the patients, signed releases of the patient or of their legal representative should be enclosed.The journal requires experimental research studies on vertebrates or any regulated invertebrates to comply with relevant institutional, national and/or international guidelines, and authors are advised to clearly state their compliance with relevant guidelines.For studies involving animals, it is required to obtain approval of research protocols from an ethics committee. The committee reviews protocols to ensure compliance with applicable regulations and guidelines, including the <a href="https://www.ncbi.nlm.nih.gov/books/NBK54050/" target="_blank">Guide for the Care and Use of Laboratory Animals (8th Edition, 2011)</a>, <a href="http://iclas.org/" target="_blank">International Council for Laboratory Animal Science (ICLAS)</a>, and the <a href="https://www.aaalac.org/resources/resources-list/" target="_blank">International Guiding Principles for Biomedical Research Involving Animals (2012)</a>. These guidelines offer comprehensive instructions on how to carry out animal research ethically and humanely and are widely acknowledged as the benchmark for such research.Authors should provide detailed explanation of the ethical treatment of animals in their manuscripts, including measures taken to avoid pain and distress. This is crucial to ensure the humane conduct of the study and enable verification that it conforms to the relevant ethical criteria. The <a href="https://arriveguidelines.org/" target="_blank">ARRIVE</a> checklist is a useful tool authors can use to present this information clearly and thoroughly.

The journal requires the authors and all individuals taking part in the evaluation process to disclose any existing or potential conflict of interest (such as financial ties, academic commitments, personal relationships, institutional affiliations) that could unduly influence one’s responsibilities.  To disclose potential conflicts of interest, the <a href="https://cdn.istanbul.edu.tr/file/JTA6CLJ8T5/94506272CF4A4E4196880083BF0A0C0F" target="_blank">ICMJE Potential Conflict of Interest Disclosure Form</a> should be filled in and submitted by authors as explained in the Author Form of the journal. Cases of a potential conflict of interest are resolved  within the scope of <a href="https://publicationethics.org/resources/flowcharts/complete-set-english" target="_blank">COPE Conflict of Interest Flowcharts </a>and<a href="https://www.icmje.org/about-icmje/faqs/conflict-of-interest-disclosure-forms/" target="_blank"> ICMJE Conflict of Interest guidelines</a>Besides conflict of interest, all financial support received to carry out research must be declared while submitting the paper.

It is authors’ responsibility to ensure that the article is in accordance with scientific and ethical standards and rules. And authors must ensure that submitted work is original. They must certify that the manuscript has not previously been published elsewhere or is not currently being considered for publication elsewhere, in any language. Applicable copyright laws and conventions must be followed. Copyright material (e.g. tables, figures or extensive quotations) must be reproduced only with appropriate permission and acknowledgement. Any work or words of other authors, contributors, or sources must be appropriately credited and referenced.All the authors of a submitted manuscript must have direct scientific and academic contribution to the manuscript. The author(s) of the original research articles is defined as a person who is significantly involved in “conceptualization and design of the study”, “collecting the data”, “analyzing the data”, “writing the manuscript”, “reviewing the manuscript with a critical perspective” and “planning/conducting the study of the manuscript and/or revising it”. Fund raising, data collection or supervision of the research group are not sufficient roles to be accepted as an author. The author(s) must meet all these criteria described above. The order of names in the author list of an article must be a co-decision and it must be indicated in the <a href="https://cdn.istanbul.edu.tr/file/JTA6CLJ8T5/186C140D668949F1B99FA496B08D8610" target="_blank">Copyright Agreement Form</a>. The individuals who do not meet the authorship criteria but contributed to the study must take place in the acknowledgement section. Individuals providing technical support, assisting writing, providing a general support, providing material or financial support are examples to be indicated in acknowledgement section.All authors must disclose all issues concerning financial relationship, conflict of interest, and competing interest that may potentially influence the results of the research or scientific judgment.When an author discovers a significant error or inaccuracy in his/her own published paper, it is the author’s obligation to promptly cooperate with the Editor to provide retractions or corrections of mistakes.

Editor-in-Chief evaluates manuscripts for their scientific content without regard to ethnic origin, gender, sexual orientation, citizenship, religious belief or political philosophy of the authors. He/She provides a fair double-blind peer review of the submitted articles for publication and ensures that all the information related to submitted manuscripts is kept as confidential before publishing.Editor-in-Chief is responsible for the contents and overall quality of the publication. He/She must publish errata pages or make corrections when needed.Editor-in-Chief does not allow any conflicts of interest between the authors, editors and reviewers. Only he has the full authority to assign a reviewer and is responsible for final decision for publication of the manuscripts in the Journal.Reviewers must have no conflict of interest with respect to the research, the authors and/or the research funders. Their judgments must be objective.Reviewers must ensure that all the information related to submitted manuscripts is kept as confidential and must report to the editor if they are aware of copyright infringement and plagiarism on the author’s side.A reviewer who feels unqualified to review the topic of a manuscript or knows that its prompt review will be impossible should notify the editor and excuse himself from the review process.The editor informs the reviewers that the manuscripts are confidential information and that this is a privileged interaction. The reviewers and editorial board cannot discuss the manuscripts with other persons. The anonymity of the referees must be ensured. In particular situations, the editor may share the review of one reviewer with other reviewers to clarify a particular point.

Only those manuscripts approved by its every individual author and that were not published before in or sent to another journal, are accepted for evaluation.Submitted manuscripts that pass preliminary control are scanned for plagiarism using iThenticate software. After plagiarism check, the eligible ones are evaluated by editor-in-chief for their originality, methodology, the importance of the subject covered and compliance with the journal scope.The editor hands over the papers matching the formal rules to at least two national/international referees for double-blind peer review evaluation and gives green light for publication upon modification by the authors in accordance with the referees’ claims.

Peer Review

Issue Type	Regular
Editor(s)	Şehnaz Bolkent
Cover (PDF)
Full Text (PDF)
Front Pages (PDF)

European Journal of Biology

VOLUME 82, ISSUE 1, 2023

In Silico Approach for Identification of PI3K/mTOR Dual Inhibitors for Multiple Myeloma Treatment