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DOI :10.26650/EurJBiol.2018.18008   IUP :10.26650/EurJBiol.2018.18008    Tam Metin (PDF)

Serum Concentration of Ghrelin, Oxidative Stress and Lipid Parameters in Obese Subjects

Sevilay Zora, Türkan Yigitbasi, Gozde Ulfer, Nesrin Emekli

Objective: Ghrelin is a hormone with peptide structure. It has fatty tissue and increases appetite. Obesity is a multifactorial chronic disease characterized by an increase in fat tissue. Fat tissue, like the endocrine organ, triggers oxidative stress and can lead to the development of obesity-related pathologies. The purpose of this study is to examine the relationship between the ghrelin in blood, and oxidative stress and lipid parameters. Materials and Methods: The study was conducted with 61 obese and 24 healthy individuals. Ghreline levels were measured using the ELISA method, while total antioxidant status (TAS) and oxidant status (TOS), triglyceride (TG), total cholesterol (TC), HDL-cholesterol (HDL-C) and LDL cholesterol (LDL-C) levels were measured using the photometric method. Results: A negative correlation was found between body mass index (BMI) and ghrelin levels in the obese group (p<0.05). But there was no significant difference of ghrelin levels in obese and control groups (p>0.05). TAS was observed to be lower in obese compared to control group, while The Oxidative Stress Index (OSI) was found to be significantly higher than the obese group (p<0.05). TG levels were found to be increased in obese; whereas ghrelin, TC, LDL-C and HDL-C levels did not show any difference (p>0.05). Conclusion: Increasing obesity level (BMI) and decreasing ghrelin level were found to be correlated. New studies are needed in order to discover the changes in ghrelin level connected to oxidative stress.
Anahtar Kelimeler: Ghrelin, obesity, oxidative stress

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APA

Zora, S., Yigitbasi, T., Ulfer, G., & Emekli, N. (2018). Serum Concentration of Ghrelin, Oxidative Stress and Lipid Parameters in Obese Subjects. European Journal of Biology, 77(2), 55-58. https://doi.org/10.26650/EurJBiol.2018.18008


AMA

Zora S, Yigitbasi T, Ulfer G, Emekli N. Serum Concentration of Ghrelin, Oxidative Stress and Lipid Parameters in Obese Subjects. European Journal of Biology. 2018;77(2):55-58. https://doi.org/10.26650/EurJBiol.2018.18008


ABNT

Zora, S.; Yigitbasi, T.; Ulfer, G.; Emekli, N. Serum Concentration of Ghrelin, Oxidative Stress and Lipid Parameters in Obese Subjects. European Journal of Biology, [Publisher Location], v. 77, n. 2, p. 55-58, 2018.


Chicago: Author-Date Style

Zora, Sevilay, and Türkan Yigitbasi and Gozde Ulfer and Nesrin Emekli. 2018. “Serum Concentration of Ghrelin, Oxidative Stress and Lipid Parameters in Obese Subjects.” European Journal of Biology 77, no. 2: 55-58. https://doi.org/10.26650/EurJBiol.2018.18008


Chicago: Humanities Style

Zora, Sevilay, and Türkan Yigitbasi and Gozde Ulfer and Nesrin Emekli. “Serum Concentration of Ghrelin, Oxidative Stress and Lipid Parameters in Obese Subjects.” European Journal of Biology 77, no. 2 (Sep. 2025): 55-58. https://doi.org/10.26650/EurJBiol.2018.18008


Harvard: Australian Style

Zora, S & Yigitbasi, T & Ulfer, G & Emekli, N 2018, 'Serum Concentration of Ghrelin, Oxidative Stress and Lipid Parameters in Obese Subjects', European Journal of Biology, vol. 77, no. 2, pp. 55-58, viewed 20 Sep. 2025, https://doi.org/10.26650/EurJBiol.2018.18008


Harvard: Author-Date Style

Zora, S. and Yigitbasi, T. and Ulfer, G. and Emekli, N. (2018) ‘Serum Concentration of Ghrelin, Oxidative Stress and Lipid Parameters in Obese Subjects’, European Journal of Biology, 77(2), pp. 55-58. https://doi.org/10.26650/EurJBiol.2018.18008 (20 Sep. 2025).


MLA

Zora, Sevilay, and Türkan Yigitbasi and Gozde Ulfer and Nesrin Emekli. “Serum Concentration of Ghrelin, Oxidative Stress and Lipid Parameters in Obese Subjects.” European Journal of Biology, vol. 77, no. 2, 2018, pp. 55-58. [Database Container], https://doi.org/10.26650/EurJBiol.2018.18008


Vancouver

Zora S, Yigitbasi T, Ulfer G, Emekli N. Serum Concentration of Ghrelin, Oxidative Stress and Lipid Parameters in Obese Subjects. European Journal of Biology [Internet]. 20 Sep. 2025 [cited 20 Sep. 2025];77(2):55-58. Available from: https://doi.org/10.26650/EurJBiol.2018.18008 doi: 10.26650/EurJBiol.2018.18008


ISNAD

Zora, Sevilay - Yigitbasi, Türkan - Ulfer, Gozde - Emekli, Nesrin. “Serum Concentration of Ghrelin, Oxidative Stress and Lipid Parameters in Obese Subjects”. European Journal of Biology 77/2 (Sep. 2025): 55-58. https://doi.org/10.26650/EurJBiol.2018.18008



ZAMAN ÇİZELGESİ


Gönderim12.07.2018
Kabul18.09.2018
Çevrimiçi Yayınlanma02.12.2018

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