References

• 1. Subramaniyan V, Fuloria S, Gupta G, et al. A review on epidermal growth factor receptor’s role in breast and nonsmall cell lung cancer. Chem Biol Interact. 2022;351:109735. doi:10.1016/j.cbi.2021.109735 google scholar
• 2. Hekmat A, Saso L, Lather V, Pandita D, Kostova I, Saboury AA. Recent advances in nanomaterials of group XIV elements of periodic table in breast cancer treatment. Pharmaceutics. 2022:14(12):2640. doi: 10.3390/pharmaceutics14122640 google scholar
• 3. Zhao R, Choi BY, Lee M-H, Bode AM, Dong Z. Implications of genetic and epigenetic alterations of CDKN2A (p16INK4a) in cancer. E Bio Medicine. 2016;8:30-39. google scholar
• 4. Al-Saran N, Subash-Babu P, Al-Nouri DM, Alfawaz HA, Al-shatwi AA. Zinc enhances CDKN2A, pRb1 expression and regulates functional apoptosis via upregulation of p53 and p21 expression in human breast cancer MCF-7 cell. Environ Toxicol Pharmacol. 2016;47:19-27. google scholar
• 5. Hou H, Sun D, Zhang X. The role of MDM2 amplification and overexpression in therapeutic resistance of malignant tumors. Cancer Cell Int. 2019;19(1):216. doi:10.1186/s12935-019-0937-4 google scholar
• 6. McGrowder DA, Miller FG, Nwokocha CR, et al. Medicinal herbs used in traditional management of breast cancer: Mechanisms of action. Medicines. 2020;7(8):47. doi:10.3390/medicines7080047 google scholar
• 7. Roshanravan N, Asgharian P, Dariushnejad H, et al. Eryngium billardieri induces apoptosis via bax gene expression in pancreatic cancer cells. Adv Pharm Bull. 2018;8(4):667-674. google scholar
• 8. Daneshzadeh MS, Abbaspour H, Amjad L, Nafchi AM. An investigation on phytochemical, antioxidant and antibacterial properties of extract from Eryngium billardieri F. Delaroche. J Food Meas Charact. 2020;14:708-715. google scholar
• 9. Esmaeili S, Irani M, Moazzeni Zehan H, Keramatian B, Tavakoli Harandi Z, Hamzeloo-Moghadam M. Cytotoxic activity of some ethnic medicinal plants from southwest of Iran. J Pharmacognosy Res. 2016;3:43-47. google scholar
• 10. Hasanbeiglu S, Hosseini K, Molavi O, Asgharian P, Tarhriz V. Eryngium billardieri extract and fractions induce apoptosis in cancerous cells. Anticancer Agents Med Chem. 2022;22(11):2189-2201. google scholar
• 11. Forouhandeh H, Rezaei Param Z, Molavi O, Asgharian P, Tarhriz V. Evaluation of anti-proliferative activity of Eryngium caucasicum on melanoma cancer cells. BMC Complement Med Ther. 2022; 22(1):134. doi:10.1186/s12906-022-03618-w google scholar
• 12. Afshari M, Malayeri AR, Mohammadshahi M. Effects of Eryngium caucasicum extract on testosterone, inflammation and oxidative status of nicotinamide-streptozotocin induced type-2 diabetes in male rats. J Contemp Med Sci. 2019;5(2):77-81. google scholar
• 13. Schmittgen TD, Livak KJ. Analyzing real-time PCR data by the comparative CT method. Nat Protoc. 2008;3(6):1101-1108. google scholar
• 14. Jarzçbski M, Siejak P, Smulek W, et al. Plant extracts containing saponins affects the stability and biological activity of hempseed oil emulsion system. Molecules. 2020;25(11):2696. doi:10.3390/molecules25112696 google scholar
• 15. Robbins RJ. Phenolic acids in foods: An overview of analytical methodology. J Agric Food Chem. 2003;51(10):2866-2887. google scholar
• 16. Abubakar AR, Haque M. Preparation of medicinal plants: Basic extraction and fractionation procedures for experimental purposes. J Pharm Bioallied Sci. 2020;12(1):1-12. google scholar
• 17. Hosseini K, Ariya MP, Molavi O, Asgharian P, Tarhriz V. The fractions of Eryngium thyrsoideum extract sensitize breast cancer cells to apoptosis. J Nat Pharm Prod. 2022;17(3):118888. doi:10.5812/jjnpp.118888 google scholar
• 18. Nordin FJ, Pearanpan L, Chan KM, et al. Immunomodulatory potential of Clinacanthus nutans extracts in the coculture of triple-negative breast cancer cells, MDA-MB-231, and THP-1 macrophages. PLoS One. 2021;16(8):e0256012. doi:10.1371/journal.pone.0256012 google scholar
• 19. Alshaeri HK, Alasmari MM, Natto ZS, Pino-Figueroa A. Effects of Annona muricata extract on triple-negative breast cancer cells mediated through EGFR signaling. Cancer Manag Res. 2020;12:12519-12526. google scholar
• 20. Nguyen ST, Nguyen HT-L, Truong KD. Comparative cytotoxic effects of methanol, ethanol and DMSO on human cancer cell lines. Biomed Res Ther. 2020;7(7):3855-3859. google scholar
• 21. Samson J, Derlipanska M, Zaheed O, Dean K. Molecular and cellular characterization of two patient-derived ductal carcinoma in situ (DCIS) cell lines, ETCC-006 and ETCC-010. BMC Cancer. 2021;21(1):1-20. google scholar
• 22. Hekmat A, Rabizadeh M, Safavi M, Hajebrahimi Z. The comparison of the apoptosis effects of titanium dioxide nanoparticles into MDA-MB-231 cell line in microgravity and gravity conditions. Nanomed J. 2019;6(2):120-127. google scholar
• 23. Pagayeva L, Kongül E, Geylan R, Karatoprak G§, Tugay O, editors. Analysis of the cytotoxic effects of Eryngium billardieri Delar. Extracts on MCF7 Cell Line. Proceedings. 2017;1:1055. doi:10.3390/proceedings1101055 google scholar
• 24. Khan MA, Siddiqui S, Ahmad I, et al. Phytochemicals from Ajwa dates pulp extract induce apoptosis in human triplenegative breast cancer by inhibiting AKT/mTOR pathway and modulating Bcl-2 family proteins. Sci Rep. 2021;11(1):10322. doi:10.1038/s41598-021-89420-z google scholar
• 25. Zahedian S, Hekmat A, Tackallou SH, Ghoranneviss M. The impacts of prepared plasma-activated medium (PAM) combined with doxorubicin on the viability of MCF-7 breast cancer cells: a new cancer treatment strategy. Rep Biochem Mol Biol. 2022;10(4):640-652. google scholar
• 26. Carpenter RL, Lo H-W. Regulation of apoptosis by HER2 in breast cancer. J Carcinog Mutagen Res. 2013;2013:1-13. doi:10.4172/2157-2518.S7-003 google scholar
• 27. Vousden KH, Prives C. Blinded by the light: the growing complexity of p53. Cell. 2009;137(3):413-431. google scholar
• 28. Yavari S, Hekmat A, Saedari S. The ethanolic extract of Eryngium billardierei F. Delaroche restrains protein glycation in human serum albumin: An in vitro study. J Serb Chem Soc. 2023, November, doi:10.2298/JSC230725091Y google scholar
• 29. Kopustinskiene DM, Jakstas V, Savickas A, Bernatoniene J. Flavonoids as anticancer agents. Nutrients. 2020;12(2):457. doi:10.3390/nu12020457 google scholar
• 30. Khan AU, Dagur HS, Khan M, Malik N, Alam M, Mushtaque M. Therapeutic role of flavonoids and in cancer prevention: Current trends and future perspectives. Eur J Med Chem Rep. 2021;3:100010. doi:10.1016/j.ejmcr.2021.100010 google scholar
• 31. Fabiani R. Anti-cancer properties of olive oil secoiridoid phenols: A systematic review of in vivo studies. Food Funct. 2016;7(10):4145-4159. google scholar

Citations